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Message: <blockquote data-quote="tim2000s" data-source="post: 1475010" data-attributes="member: 30007">IA2 is Islet Cell Autoantibodies, and is one of the indicators that the body is attacking the islet cells. GAD is Glutamic Acid Decarboxylase Autoantibodies. which are an indication of an immune system attack. ZnT8 is an islet beta-cell secretory granule membrane protein, and a Zn8 Autoantibody is another indicator of an immune attack on the beta cells.Details of the overlap can be found in this report: <a href="https://www.ncbi.nlm.nih.gov/pubmed/19808923" target="_blank">https://www.ncbi.nlm.nih.gov/pubmed/19808923</a>That's why they are doing all these tests - if you have these antibodies, they indicate type 1 diabetes. That's all really!</blockquote>

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