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<blockquote data-quote="janabelle" data-source="post: 93531" data-attributes="member: 7788"><p>Hi Gbswales,</p><p>I am a long-term type-1 and experienced a similar problem on Lantus. It doesn't work for some people, me included. Test have shown that a significant percentage of Lantus can remain at the injection site for up to 36 hours after injection. This explains why it seems to work some days, and not on other days. I suffered over 4 years of these ups and downs, with no help from my diabetes clinic, despite reporting it many times. </p><p></p><p>It constantly surprises me that when people are having problems with Lantus, doctors are so reluctant to change it for an alternative, especially when there are many other long-acting insulins available.</p><p></p><p>Lantus has not been tested safe on pregnant women, and children under 6, yet it is prescribed freely to both. Lantus clinical trials were only carried out over a period of 28 weeks for type-1s, however patients report problems with control and other side effects even as long as 18-24 months after starting taking Lantus. The results of these trials were only based on HBA1c results,which were measured, against another synthetic insulin. When I complained to my diabetes consultant that my BGs were fluctuating between approx 2- 15 every day(sometimes higher), the problem was ignored because my HBA1c was within the normal range, which really made me doubt the value of this test.</p><p></p><p>I tried many things to keep consistent control while on Lantus, but nothing, diet, excercise or adjusting my doses worked, it was constantly unpredictable. I changed to Hyprurin Porcine Isophane in May 2008, and I have had daily consistent, predictable control since,so there is no doubt in my mind that Lantus doesn't work. I also feel so much better.</p><p>You should contact the IDDT (insulin dependent diabetes trust) for advice, they have a helpline numer on their website.</p><p>Best of luck</p><p>Jus</p></blockquote><p></p>
[QUOTE="janabelle, post: 93531, member: 7788"] Hi Gbswales, I am a long-term type-1 and experienced a similar problem on Lantus. It doesn't work for some people, me included. Test have shown that a significant percentage of Lantus can remain at the injection site for up to 36 hours after injection. This explains why it seems to work some days, and not on other days. I suffered over 4 years of these ups and downs, with no help from my diabetes clinic, despite reporting it many times. It constantly surprises me that when people are having problems with Lantus, doctors are so reluctant to change it for an alternative, especially when there are many other long-acting insulins available. Lantus has not been tested safe on pregnant women, and children under 6, yet it is prescribed freely to both. Lantus clinical trials were only carried out over a period of 28 weeks for type-1s, however patients report problems with control and other side effects even as long as 18-24 months after starting taking Lantus. The results of these trials were only based on HBA1c results,which were measured, against another synthetic insulin. When I complained to my diabetes consultant that my BGs were fluctuating between approx 2- 15 every day(sometimes higher), the problem was ignored because my HBA1c was within the normal range, which really made me doubt the value of this test. I tried many things to keep consistent control while on Lantus, but nothing, diet, excercise or adjusting my doses worked, it was constantly unpredictable. I changed to Hyprurin Porcine Isophane in May 2008, and I have had daily consistent, predictable control since,so there is no doubt in my mind that Lantus doesn't work. I also feel so much better. You should contact the IDDT (insulin dependent diabetes trust) for advice, they have a helpline numer on their website. Best of luck Jus [/QUOTE]
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