My son uses the Inset II's with 6mm sets. I am fascinated to read these posts about the glitches that people have with them.
My son has used them for about 2 1/2 years now and I think we have had no more than 2 failed sets - and that has been because blood has entered the cannula, so we've changed the set as a precaution. We have never actually had an occlusion alarm on the current pump - and we have the sensitivity set to high.
However, he did have an Animas Pump to begin with, which just lost prime and alarmed all the time, plus it gave him hypos after every time he re-primed it - which was really dodgy - so Animas replaced the pump under warranty and no more probs.
Also have never needed to adjust rates before or after set-change - just fill the cannula and off he goes. He does sometimes complain that the mechanism doesn't fire properly, in which case he will bin the set and try another one.
He uses 'Skin Tac' wipes (from Animas) to help keep the set stuck on nicely - seems to work very well but is a nightmare to wash off fingers!