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Insulin, Glucagon, and Gluconeogenesis

Jo_the_boat

Jo_the_boat

Well-Known Member
Messages
809
Location
Littleborough, Lancashire
Type of diabetes
Type 2
Treatment type
Diet only
OK, here's a summary of a series of notes Micheal Eades MD has posted over the past few weeks.
I'm sure some of the more studious among you will find it interesting.

Here's the link.

If you can't open it, does anyone know another way to access it?
I can copy it to my own website at a push, but it's worth making it available for people to look at.
 
I could open it, but maybe that was because I've opened stuff from there before when you posted links?
I did read this but it is a bit above me
 
The science bit refers to rat studies. The rodent has a distributed pancreas, whereas the human has a single organ. Also the rat has many times the Beta Cell capacity than the human whereas the human has more alpha cells (which secrete glucagon) and which detect and trigger the insulin response.. The rat has larger Isle of Langerhans. So the etiology of insulin resistance is different, which the article does not allow for. Making like for like comparisons is no longer a safe assumption to make when reviewing rodent studies, and the read across is not quite so gold plated.
 
Jo_the_boat said:
OK, here's a summary of a series of notes Micheal Eades MD has posted over the past few weeks.
I'm sure some of the more studious among you will find it interesting.

Here's the link.

If you can't open it, does anyone know another way to access it?
I can copy it to my own website at a push, but it's worth making it available for people to look at.
Click to expand...
Worked for me and I've signed up to the weekly Arrow . Thanks for bringing this to my attention....Off for a cup of coffee and a read now!
 
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