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Insulin overdose in non-diabetic
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<blockquote data-quote="SimonCrox" data-source="post: 1428192" data-attributes="member: 388174"><p>Annoying problem to put it mildly.</p><p>25% care home residents have diabetes of whom half are known; so there is a 12% chance that your dad has diabetes and it is not known. So if he is a bit tubby, and has undiagnosed T2DM, might not be too much of a problem</p><p>But if he is skinny, and not diabetic, then his glucose levels could drop signficantly.</p><p>As above, the hospital would but on a glucose drip and watch the glucose levels carefully.</p><p>The scope for problems lies in the duration of effect of the lantus; folk would say a 24 hour duration of effect, but it can last for longer eg the 24 hours is the therpeutic effect in standard doses, but a big (much bigger than 17 units) can make folk hypo for days, eg 5 days.</p><p>So, if a quick acting insulin, he would need a fair bit of CHO to avoid hypos but should be sorted by 24 hours; but if Lantus, would not need such a rapid rate of CHO ingestion, but it could go on for longer and one would want your dad to be OK off any glucose drip for 24 hours.</p><p>If his renal function is poor, and the routine measures of renal function in a frail older person underestimate the proble, then the insulin will hang around for longer.</p><p>Safeguarding concerns will be raised (appropriately) and their investigation will probably keep your dad in hospital a few days more.</p><p>Best wishes</p></blockquote><p></p>
[QUOTE="SimonCrox, post: 1428192, member: 388174"] Annoying problem to put it mildly. 25% care home residents have diabetes of whom half are known; so there is a 12% chance that your dad has diabetes and it is not known. So if he is a bit tubby, and has undiagnosed T2DM, might not be too much of a problem But if he is skinny, and not diabetic, then his glucose levels could drop signficantly. As above, the hospital would but on a glucose drip and watch the glucose levels carefully. The scope for problems lies in the duration of effect of the lantus; folk would say a 24 hour duration of effect, but it can last for longer eg the 24 hours is the therpeutic effect in standard doses, but a big (much bigger than 17 units) can make folk hypo for days, eg 5 days. So, if a quick acting insulin, he would need a fair bit of CHO to avoid hypos but should be sorted by 24 hours; but if Lantus, would not need such a rapid rate of CHO ingestion, but it could go on for longer and one would want your dad to be OK off any glucose drip for 24 hours. If his renal function is poor, and the routine measures of renal function in a frail older person underestimate the proble, then the insulin will hang around for longer. Safeguarding concerns will be raised (appropriately) and their investigation will probably keep your dad in hospital a few days more. Best wishes [/QUOTE]
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