Insulin Resistance clinic at Addenbrookes

Leptin is a satiety hormone. Not sure why you'd want to block that. Are we perhaps getting it confused with ghrelin? Also, I thought lipodystrophy is a relative inability to get fat? Sorry, not trying to be "that guy" or anything. I'm just a little concerned that I'm losing the plot or catastrophically misreading

I hv no experience of attending an IR clinic (anywhere) but my diabesity clinic has assisted my huge IR with the opportunity of bariatric surgery in Sunderland. Its working very very well. So far.
IR combat courses should be available on-line via the NHS but it isn't, yet. It's mentioned and states advice which is mainly, lose weight.
I feel for me that had to come otherwise I faced a painful death. I was over 22st at one point. I'm now 15½ with far far better IR but not cured as I still hv loads of mid core body fat. My liver improved but is having a silly moment.
The liver is the catalyst of IR. Fix the bad performing liver and a better aid than assisting leptin resistance etc.

ickihun said:

The liver is the catalyst of IR.

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Yep. Starts in the liver when it begins running out of places to put fat and has to start rejecting the glucose instead.

Emmasndco said:

So, as I feared, I don’t meet the referral criteria as my BMI is over 30. Gutted

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To be honest, if you need to be under a certain BMI in order to qualify for attendance at an insulin resistance clinic, then it was probably never worth going in the first place.