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Insulin to Carb Ratios at Different Times of Day
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<blockquote data-quote="Cheryl" data-source="post: 221893" data-attributes="member: 35617"><p>I know where you are coming from Donnellysdogs, 2-3 hours is the peak time of activity for human analogs (I use Humalog) but when you look at the activity graphs for it they show that it starts working after about 10 mins, hits peak performance at about 60 mins, stays there for the next 2 hours then trails off over hour 3 to 4, but still has some effect, though only a little for another 2 hours. It doesn't leave one's system fully until about 6 hours from infusion. (data from Ely Lilly's own site) </p><p></p><p>For me, peak hypo risk always seems to be 4-5 hours after a bolus. Different people absorb at different rates of course & I am somewhat atypical (as usual) as I appear to absorb quite slowly. Pumps with bolus wizards allow one to set one's own insulin curve (for the pump's insulin on board calculation) in recognition of this I assume. </p><p></p><p>I also have to bolus, if possible, at least 30 mins before a meal to try to stop big spikes afterwards. I still spike into double figures every meal, but if I have more insulin, I'm hypo 4-5 hours after my meal.</p><p></p><p>Thanks for your input, it's useful to know that I'm not alone in being the opposite of what the HCPs tell me is normal...again!</p></blockquote><p></p>
[QUOTE="Cheryl, post: 221893, member: 35617"] I know where you are coming from Donnellysdogs, 2-3 hours is the peak time of activity for human analogs (I use Humalog) but when you look at the activity graphs for it they show that it starts working after about 10 mins, hits peak performance at about 60 mins, stays there for the next 2 hours then trails off over hour 3 to 4, but still has some effect, though only a little for another 2 hours. It doesn't leave one's system fully until about 6 hours from infusion. (data from Ely Lilly's own site) For me, peak hypo risk always seems to be 4-5 hours after a bolus. Different people absorb at different rates of course & I am somewhat atypical (as usual) as I appear to absorb quite slowly. Pumps with bolus wizards allow one to set one's own insulin curve (for the pump's insulin on board calculation) in recognition of this I assume. I also have to bolus, if possible, at least 30 mins before a meal to try to stop big spikes afterwards. I still spike into double figures every meal, but if I have more insulin, I'm hypo 4-5 hours after my meal. Thanks for your input, it's useful to know that I'm not alone in being the opposite of what the HCPs tell me is normal...again! [/QUOTE]
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