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Diabetes Discussion
Type 1.5/LADA Diabetes
Interpreting urine cpeptide/creatinine ratio
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<blockquote data-quote="ert" data-source="post: 2432031" data-attributes="member: 504712"><p>You need to use the HOMA calculations which are more helpful as they show deterioration of beta cells as a percentage. (What my specialist used normally but my insulin production was too low to use the formulas when I was first diagnosed.) Otherwise, you will have to keep having c-peptide tests, and just having inconclusive results, waiting until the day you only have trace insulin (c-peptide below 0.2 ng/ml) and high blood sugars.</p><p></p><p>The deterioration of beta cells isn't linear for type 1's. On diagnosis, my c-peptide was 0.17 ng/ml (type 1 diagnosis below 0.2) and blood sugar 18 mmol/l. I got my blood sugars down through low carb and running and one meal a day. My c-peptide plateaued for 2 years without changing. Then overnight my blood sugars shot up high with ketones of 5+, and I needed insulin and my c-peptide was 0.078 ng/ml (which is producing no insulin). I had GAD antibodies again (the first lot disappeared after 6 months) which supports my immune system killed off the rest of my beta cells. They did not deteriorate I just had two separate autoimmune responses killing them off on two different dates. This is on my specialist's report. I have private medical insurance so had an appointment every 3 months after I was diagnosed until I started insulin. I'm just looked after by the hospital team now (but my specialist is the head of the hospital team.)</p><p><a href="https://www.dtu.ox.ac.uk/homacalculator/" target="_blank">https://www.dtu.ox.ac.uk/homacalculator/</a></p></blockquote><p></p>
[QUOTE="ert, post: 2432031, member: 504712"] You need to use the HOMA calculations which are more helpful as they show deterioration of beta cells as a percentage. (What my specialist used normally but my insulin production was too low to use the formulas when I was first diagnosed.) Otherwise, you will have to keep having c-peptide tests, and just having inconclusive results, waiting until the day you only have trace insulin (c-peptide below 0.2 ng/ml) and high blood sugars. The deterioration of beta cells isn't linear for type 1's. On diagnosis, my c-peptide was 0.17 ng/ml (type 1 diagnosis below 0.2) and blood sugar 18 mmol/l. I got my blood sugars down through low carb and running and one meal a day. My c-peptide plateaued for 2 years without changing. Then overnight my blood sugars shot up high with ketones of 5+, and I needed insulin and my c-peptide was 0.078 ng/ml (which is producing no insulin). I had GAD antibodies again (the first lot disappeared after 6 months) which supports my immune system killed off the rest of my beta cells. They did not deteriorate I just had two separate autoimmune responses killing them off on two different dates. This is on my specialist's report. I have private medical insurance so had an appointment every 3 months after I was diagnosed until I started insulin. I'm just looked after by the hospital team now (but my specialist is the head of the hospital team.) [URL]https://www.dtu.ox.ac.uk/homacalculator/[/URL] [/QUOTE]
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Type 1.5/LADA Diabetes
Interpreting urine cpeptide/creatinine ratio
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