I wonder if glucose is central to the three great epidemics of our time; obesity, diabetes, and non-alcoholic fatty liver (20% of the population)
With The Department of Obesity and Endocrinology, Liverpool University and Prof Feinman of New York we have researched a practical response to try and help some of the folk with abnormal liver function, many of whom have T2D by using a lower carb, higher fat diet; published here
http://bit.ly/1NYsS6x
The work has taken three years and was nearly fully funded by us in the practice. Please pass it on if you feel it has any merit.
Essentially when the liver glucose stores are full any more dietary glucose has to be cleared somehow-so the liver converts it to fat – fatty liver. Prof Taylor feels this fat and similar fat in the pancreas explains why (I love this quote.)
‘Before diagnosis of Type 2 diabetes, there is
a long silent scream from the liver.
As the fat interferes with the normal functioning of both organs.
The good news is this process could be reversible and may possibly in part help explain how reducing the glucose in the diet can improve liver function, insulin sensitivity and obesity.
Certainly the patients in the study had the GGT liver blood test improve by an average of 47%. Reading this it looks a huge claim- makes me nervous. Anyway read the paper for more, but bear in mind I am not an academic only a GP and it’s just a pilot study.
Excellent article and I agree. (retired body builder and graduate Biologist). The problems started when we switched from fats to carbs back in the 70's(?) The 5 a day campaign made it worse. Most people will reach for sugary fruit rather than green vegetables. We are a nation of sugar junkies. Diabetes will be the biggest threat health wise and financially to the NHS. I will follow you on twitter.
Thanks to my wife Jen I can now be followed on twitter @lowcarbGP