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Diabetes Discussion
Type 1.5/LADA Diabetes
Is it possible to have LADA/1.5 with high C peptide?
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<blockquote data-quote="Chris24Main" data-source="post: 2742489" data-attributes="member: 585131"><p>OK - thanks for being so open.</p><p>I think we're in very broad agreement. </p><p>For what it's worth, I got an antibody test on initial diagnosis, but only was told the results after about 8 months - and they were inconclusive. At the time I was clueless, and don't even recall the numbers - but I was told that there were 5 antibodies - 4 with tests and I was negative to 2 of them; so just not clear enough to be sure of anything. It was not considered safe to change treatment on that basis, and it was only in conjunction with the C-Peptide test that I was re-diagnosed. Very much not a simple thing though, and as I say, I do feel extremely lucky on that front. </p><p></p><p>But - I totally accept your central point - physiologically there is a difference. </p><p>There was a very strong assumption that my pancreas was going down either way, but I'm now totally focused on insulin resistance and mitochondrial health, so I can't really speak to insult to the pancreas. One thing I keep meaning to chase down - is why the β cells are affected and not the Glucagon producing α cells - or maybe they are too.. and also the evidence that many auto-immune conditions seem to respond to lowering inflammation that comes with lowering glucose and insulin resistance (well, more than that.. but these are all now points of interest, and I sound more like an interested enthusiast, not someone searching for better understanding of his own condition).</p><p></p><p>anyway - good luck and long may the honeymoon last..!!</p></blockquote><p></p>
[QUOTE="Chris24Main, post: 2742489, member: 585131"] OK - thanks for being so open. I think we're in very broad agreement. For what it's worth, I got an antibody test on initial diagnosis, but only was told the results after about 8 months - and they were inconclusive. At the time I was clueless, and don't even recall the numbers - but I was told that there were 5 antibodies - 4 with tests and I was negative to 2 of them; so just not clear enough to be sure of anything. It was not considered safe to change treatment on that basis, and it was only in conjunction with the C-Peptide test that I was re-diagnosed. Very much not a simple thing though, and as I say, I do feel extremely lucky on that front. But - I totally accept your central point - physiologically there is a difference. There was a very strong assumption that my pancreas was going down either way, but I'm now totally focused on insulin resistance and mitochondrial health, so I can't really speak to insult to the pancreas. One thing I keep meaning to chase down - is why the β cells are affected and not the Glucagon producing α cells - or maybe they are too.. and also the evidence that many auto-immune conditions seem to respond to lowering inflammation that comes with lowering glucose and insulin resistance (well, more than that.. but these are all now points of interest, and I sound more like an interested enthusiast, not someone searching for better understanding of his own condition). anyway - good luck and long may the honeymoon last..!! [/QUOTE]
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Type 1.5/LADA Diabetes
Is it possible to have LADA/1.5 with high C peptide?
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