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Is no increase OK / healthy..?
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<blockquote data-quote="catinahat" data-source="post: 2509569" data-attributes="member: 155453"><p>The half life is the amount of time it takes the active ingredient in your body to reduce by half.</p><p>Metformin is detectable for around 96hr's in blood and saliva and up to 4 days in urine</p><p><a href="https://druggenius.com/half-life/metformin/" target="_blank">https://druggenius.com/half-life/metformin/</a></p><p>The reason you take metformin with meals is because the gastric side effects would be more likely on a empty stomach. Metformin works by reducing the amount of glucose your liver releases it does not reduce the amount of glucose in your blood from your meal. For that you would need stronger meds like jardiance or forxiga that make you pee out the excess sugar or gliclazide that forces your pancreas to produce extra insulin </p><p></p><p></p><p>There are always exceptions of course and a lot depends on the fat content of the meal because fat slows the digestion and can cause the carbs to hit the blood later. But generally speaking someone with a fully working pancreas and no insulin resistance will see their blood sugar return to pre meal levels within 2 hours. That's why we use the 2hr test as a benchmark.</p></blockquote><p></p>
[QUOTE="catinahat, post: 2509569, member: 155453"] The half life is the amount of time it takes the active ingredient in your body to reduce by half. Metformin is detectable for around 96hr's in blood and saliva and up to 4 days in urine [URL]https://druggenius.com/half-life/metformin/[/URL] The reason you take metformin with meals is because the gastric side effects would be more likely on a empty stomach. Metformin works by reducing the amount of glucose your liver releases it does not reduce the amount of glucose in your blood from your meal. For that you would need stronger meds like jardiance or forxiga that make you pee out the excess sugar or gliclazide that forces your pancreas to produce extra insulin There are always exceptions of course and a lot depends on the fat content of the meal because fat slows the digestion and can cause the carbs to hit the blood later. But generally speaking someone with a fully working pancreas and no insulin resistance will see their blood sugar return to pre meal levels within 2 hours. That's why we use the 2hr test as a benchmark. [/QUOTE]
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