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Is NO insulin in the body the ONLY cause of DKA?!
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<blockquote data-quote="janabelle" data-source="post: 157794" data-attributes="member: 7788"><p>Sparkypony & Angeldust,</p><p></p><p>Angeldust you stated that your BG was normal when you went into DKA, and from what I read about DKA I'm not surprised your doctors are puzzled.</p><p>Levemir is NOT insulin, it is a copy of insulin , a drug which lowers blood sugar levels. I just wonder whether there is something lacking in this drug which although your BG is not high, causes you to suffer DKA. </p><p> Angeldust you said "Here's proof for you that it's not the insulin: a couple of weeks back I had a gastroparesis flareup. Vomitting nonstop for the day, and in that entire time my BG did not go over 7. I took my full dose of levemir." Sparkypony you said "I do wonder though whether it would apply to me as I've been on Levemir for a good few years now, although the dosages have increased dramatically over the past few months, from only 30u at night to a whopping 74u at night and 20u in the morning."</p><p>I know Levemir is different from Lantus, which I had problems with, but they took a while to show themselves, and the most common time period for people experiencing problems (or realising it)with analogues is 18 months or over, which is why they're often not recognised.</p><p></p><p>Personally I have no experience of DKA, not even at diagnosis nearly 22 years ago. Since that time I have had 3 pregnancies , severe flu many times and the usual run of the milll illnesses. After reading both your stories I feel very lucky, it sounds absolutely horrendous.</p><p>Someone suggested recently on this forum that the probs people suffer asscociated with analogue insulins are an "allergic reaction" which I don't entirely believe but then everyone reacts differently to medications, so it's not beyond the realms of possiblity. But were that to be the case, it could be possible that you have both developed some sort of reaction which is resulting in your DKA, even though your BG is "normal"-ish and you have been taking your medication.</p><p></p><p>Analogue insulins have not been around for long, we are (I was) the long-term studies, maybe this is totally new ground for medics and hence the confustion.</p><p></p><p>I could be barking up completely the wrong tree,but after reading up on DKA I'm as puzzled as you both are. Of course not everyone on Levemir OR other analogue insulins suffer DKA in the way you both do, but we are all different, and I feel it's worth considering.</p><p>Whatever the cause, I hope you both get it sorted and don't have to suffer this anymore</p><p>Jus</p></blockquote><p></p>
[QUOTE="janabelle, post: 157794, member: 7788"] Sparkypony & Angeldust, Angeldust you stated that your BG was normal when you went into DKA, and from what I read about DKA I'm not surprised your doctors are puzzled. Levemir is NOT insulin, it is a copy of insulin , a drug which lowers blood sugar levels. I just wonder whether there is something lacking in this drug which although your BG is not high, causes you to suffer DKA. Angeldust you said "Here's proof for you that it's not the insulin: a couple of weeks back I had a gastroparesis flareup. Vomitting nonstop for the day, and in that entire time my BG did not go over 7. I took my full dose of levemir." Sparkypony you said "I do wonder though whether it would apply to me as I've been on Levemir for a good few years now, although the dosages have increased dramatically over the past few months, from only 30u at night to a whopping 74u at night and 20u in the morning." I know Levemir is different from Lantus, which I had problems with, but they took a while to show themselves, and the most common time period for people experiencing problems (or realising it)with analogues is 18 months or over, which is why they're often not recognised. Personally I have no experience of DKA, not even at diagnosis nearly 22 years ago. Since that time I have had 3 pregnancies , severe flu many times and the usual run of the milll illnesses. After reading both your stories I feel very lucky, it sounds absolutely horrendous. Someone suggested recently on this forum that the probs people suffer asscociated with analogue insulins are an "allergic reaction" which I don't entirely believe but then everyone reacts differently to medications, so it's not beyond the realms of possiblity. But were that to be the case, it could be possible that you have both developed some sort of reaction which is resulting in your DKA, even though your BG is "normal"-ish and you have been taking your medication. Analogue insulins have not been around for long, we are (I was) the long-term studies, maybe this is totally new ground for medics and hence the confustion. I could be barking up completely the wrong tree,but after reading up on DKA I'm as puzzled as you both are. Of course not everyone on Levemir OR other analogue insulins suffer DKA in the way you both do, but we are all different, and I feel it's worth considering. Whatever the cause, I hope you both get it sorted and don't have to suffer this anymore Jus [/QUOTE]
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Is NO insulin in the body the ONLY cause of DKA?!
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