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Is the CIM really dead or...
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<blockquote data-quote="Beating-My-Betes" data-source="post: 2459180" data-attributes="member: 532959"><p>Thanks!</p><p></p><p>You keep going with the mixed messages. On one hand, you point to a "complex relationship between[...]" CIM and energy balance, but then suggest that "all the variables are heavily influenced by CIM". I don't think that's true. Can insulin be thought of as "the gatekeeper of energy storage and partitioning."? Sure! Is it meaningful in the context of a body that's trying to scavenge stored-energy due to a deficit of incoming food? No!</p><p></p><p>Even if, in that moment, fat is being stored, the very fact hat the body needs to start emptying stores to keep ploughing through the day means it's gonna be accessed straight-away, no? Kinda like depositing money with the teller inside a bank, then walking outside and withdrawing the dame amount of money from the 'hole-in-the-wall' <img src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" class="smilie smilie--sprite smilie--sprite2" alt=";)" title="Wink ;)" loading="lazy" data-shortname=";)" /> I've asked you before whether the body would look to store energy for the future, when it didn't have enough for the 'current' day. I can't remember your answer.</p><p></p><p>Of course, that's only talking about weight-loss. But in terms of initial weight-gain, I don't see how insulin is any more than just a cog in a big wheel. Certainly, there are hundreds of millions of folk who live on this planet that are neither obese nor overweight, who don't avoid carbs. </p><p></p><p>Also - and I think this is really important to stress - obesity (Something I see as fundamentally distinct from being a bit overweight) has in many/most cases very little to do with the actual food. Looking at eh obesity epidemic from a purely metabolic/energy point-of-view is likely never really going to cut it</p></blockquote><p></p>
[QUOTE="Beating-My-Betes, post: 2459180, member: 532959"] Thanks! You keep going with the mixed messages. On one hand, you point to a "complex relationship between[...]" CIM and energy balance, but then suggest that "all the variables are heavily influenced by CIM". I don't think that's true. Can insulin be thought of as "the gatekeeper of energy storage and partitioning."? Sure! Is it meaningful in the context of a body that's trying to scavenge stored-energy due to a deficit of incoming food? No! Even if, in that moment, fat is being stored, the very fact hat the body needs to start emptying stores to keep ploughing through the day means it's gonna be accessed straight-away, no? Kinda like depositing money with the teller inside a bank, then walking outside and withdrawing the dame amount of money from the 'hole-in-the-wall' ;) I've asked you before whether the body would look to store energy for the future, when it didn't have enough for the 'current' day. I can't remember your answer. Of course, that's only talking about weight-loss. But in terms of initial weight-gain, I don't see how insulin is any more than just a cog in a big wheel. Certainly, there are hundreds of millions of folk who live on this planet that are neither obese nor overweight, who don't avoid carbs. Also - and I think this is really important to stress - obesity (Something I see as fundamentally distinct from being a bit overweight) has in many/most cases very little to do with the actual food. Looking at eh obesity epidemic from a purely metabolic/energy point-of-view is likely never really going to cut it [/QUOTE]
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