You are progressing well...
The morning rise is due to the Dawn Phenomenon, where our insulin resistant liver don't respond to the background insulin to hold back the glucose.
Two things you can do to mitigate dawn phenomenon. Firstly do plenty of mild exercise in order to keep glycogen levels low (glycogen is glucose stored in your liver and muscles). Training with weights both depletes glycogen and sucks up lots of glucose.
I was under the impression that depleting glycogen stores only results in them filling up again next time you eat.
Why would you want to remove stored glycogen? If there is insufficient glycogen, and no food source of glucose, then muscle tissue and fat will be broken down through catabolic hormones such as cortisol to maintain sufficient glucose supply to the brain. This catabolism is mal-adaptive, ie meant to be a quick fix, not a long term solution, and creates its own problems through long term stress response.
No, if the body senses it has insufficient glucose, then it results in cortisol being released to break down muscle tissue and fat to release glucose (gluconeogenesis). Excess, prolonged high cortisol has impact on brain, heart, skin, sleep, etc. The brain primarily runs on glucose as preferential energy source, so we need it http://neuro.hms.harvard.edu/harvar...n-newsletter/and-brain-series/sugar-and-brain
May I ask if you are a diabetic, a scientist, a health care professional? You have no details on your profile page and only joined yesterday. It would be interesting to know where you are coming from with your very scientific posts and what interest you have in this forum. Genuine questions.
Why would you want to remove stored glycogen?
Diabetes is characterised by too much glucose in the body. The solution is to remove the glucose, not put more in. But I guess whatever works for the individual
OK, i'm still reading about this, so my opinion below is definitely not fully-formed, and will probably be contentious
But I would say that Diabetes is diagnosed by too much glucose in the body. That's a symptom of the issue, not a cause. The solution is to train the body to metabolise glucose through proper oxidative metabolism, not simply remove glucose.
As my post above said, it's the equivalent of saying "i get pain after doing weights at the gym. So the solution is not to go to the gym any more". Rather than training yourself to be able to handle doing that weight training. Thoughts?
If you train your body to metabolise fat/fatty acids, then by definition you remain insulin resistant. Randle Cycle etc..
Anyway, it's late!
High glucose does not come first. It all starts with high insulin levels. This in turn creates insulin resistance. Insulin resistance requires even more insulin to "clear" the ingested glucose from the blood stream. Vicious circle. This can go on for decades before glucose levels are high enough for a T2 diagnosis. Meanwhile, as insulin is a fat carrying hormone various things happen and weight gain ensues in many people. (not all). The weight gain is a symptom, not a cause. So if high insulin levels are stage 1, it makes sense to reduce the insulin levels. The best way to do this is by reducing/avoiding foods that cause insulin spikes. These foods are mainly starchy carbs and fruit, although other foods are also insulinogenic. (Happily, butter creates absolutely zero insulin spikes.). Reduce the need for insulin = less or no insulin resistance = normal glucose levels. As a bonus, many also lose the weight.
OK, i'm still reading about this, so my opinion below is definitely not fully-formed, and will probably be contentious
But I would say that Diabetes is diagnosed by too much glucose in the body. That's a symptom of the issue, not a cause. The solution is to train the body to metabolise glucose through proper oxidative metabolism, not simply remove glucose.
As my post above said, it's the equivalent of saying "i get pain after doing weights at the gym. So the solution is not to go to the gym any more". Rather than training yourself to be able to handle doing that weight training. Thoughts?
If you train your body to metabolise fat/fatty acids, then by definition you remain insulin resistant. Randle Cycle etc..
Anyway, it's late!
Gluconeogenesis is a demand driven process that uses dietary protein to make glucose to fuel the brain if and when required. The brain can also run on ketones which is what it does when ketosis is achieved by reducing dietary carbohydrate to a minimum.then it results in cortisol being released to break down muscle tissue and fat to release glucose (gluconeogenesis).
I'm quite shocked that the solution seems to be "don't eat much glucose", since it doesn't treat the underlying issue. It's like saying "I used to get sore from going to the gym, but i'm over that now, since I no longer go to the gym".
Fair questions
I'm not a scientist per se, but have studied it personally for a number of years. I'm still a rank amateur, and don't pretend to be otherwise. My interest in the forum came from a recent bout of illness (about 5 weeks ago), followed by some bad/sporadic eating, and then I found a blood glucose meter I had at home, and tested myself over the course of a couple of weeks after illness, and found that my fasting BG was up above 10 on multiple occasions. One day it was 12. And my BG was spiking massively after meals for about 2 weeks (again, around 10-12 quite often). I was testing myself around 4-5 times a day, and found that I rarely got below 6, and was often at 8 mmol even a few hours after meals.
So I did some googling, and found various web pages, and forums, which were basically saying I "have diabetes". And frankly, I found most of the pages to be nonsense. And then started reading more about insulin, insulin resistance, and the link to the incredibly lucrative insulin industry, and started testing various things out. I began tracking calories, meal timings, and adding in various supplements I was reading about: magnesium, biotin, aspirin, upping my dose of thyroid hormone, sodium, potassium, fixing breathing patterns etc... and found my fasting BG and postprandial coming down quickly to "pre-diabetic" to "normal" levels. My fasting BG this morning was 5.5, for example, and 1.5 hour postprandial on a meal today was 5.8. So whatever I'm doing is working. Not had hba1c measured yet, but I will. It's clear that insulin is not the only thing that affects BG, yet most of the sciencey pages only talk about it. It seems weird.
So i'm sorta here to figure out if I "have diabetes" like a website said based on my BG numbers from a few weeks ago, (and apparently today don't have diabetes!), and see what other people are doing. I'm quite shocked that the solution seems to be "don't eat much glucose", since it doesn't treat the underlying issue. It's like saying "I used to get sore from going to the gym, but i'm over that now, since I no longer go to the gym". No one talks about glycolysis, gluconeogenesis, the Randle cycle, CO2 production, lactate, cortisol, adrenaline, calcium, oxidative metabolism, thyroid etc. It's all LCHF. It's weird. I'm not here to preach, I just find it interesting for some reason. I tend to get quite into a topic for a while, then move on
But I guess if I can't keep my BG under control, or the hba1c comes back bad, then I'll have to reconsider my positions!
Hi,Fair questions
I'm not a scientist per se, but have studied it personally for a number of years. I'm still a rank amateur, and don't pretend to be otherwise. My interest in the forum came from a recent bout of illness (about 5 weeks ago), followed by some bad/sporadic eating, and then I found a blood glucose meter I had at home, and tested myself over the course of a couple of weeks after illness, and found that my fasting BG was up above 10 on multiple occasions. One day it was 12. And my BG was spiking massively after meals for about 2 weeks (again, around 10-12 quite often). I was testing myself around 4-5 times a day, and found that I rarely got below 6, and was often at 8 mmol even a few hours after meals.
So I did some googling, and found various web pages, and forums, which were basically saying I "have diabetes". And frankly, I found most of the pages to be nonsense. And then started reading more about insulin, insulin resistance, and the link to the incredibly lucrative insulin industry, and started testing various things out. I began tracking calories, meal timings, and adding in various supplements I was reading about: magnesium, biotin, aspirin, upping my dose of thyroid hormone, sodium, potassium, fixing breathing patterns etc... and found my fasting BG and postprandial coming down quickly to "pre-diabetic" to "normal" levels. My fasting BG this morning was 5.5, for example, and 1.5 hour postprandial on a meal today was 5.8. So whatever I'm doing is working. Not had hba1c measured yet, but I will. It's clear that insulin is not the only thing that affects BG, yet most of the sciencey pages only talk about it. It seems weird.
So i'm sorta here to figure out if I "have diabetes" like a website said based on my BG numbers from a few weeks ago, (and apparently today don't have diabetes!), and see what other people are doing. I'm quite shocked that the solution seems to be "don't eat much glucose", since it doesn't treat the underlying issue. It's like saying "I used to get sore from going to the gym, but i'm over that now, since I no longer go to the gym". No one talks about glycolysis, gluconeogenesis, the Randle cycle, CO2 production, lactate, cortisol, adrenaline, calcium, oxidative metabolism, thyroid etc. It's all LCHF. It's weird. I'm not here to preach, I just find it interesting for some reason. I tend to get quite into a topic for a while, then move on
But I guess if I can't keep my BG under control, or the hba1c comes back bad, then I'll have to reconsider my positions!
I began tracking calories, meal timings, and adding in various supplements I was reading about: magnesium, biotin, aspirin, upping my dose of thyroid hormone, sodium, potassium, fixing breathing patterns etc... and found my fasting BG and postprandial coming down quickly to "pre-diabetic" to "normal" levels. My fasting BG this morning was 5.5, for example, and 1.5 hour postprandial on a meal today was 5.8. So whatever I'm doing is working. Not had hba1c measured yet, but I will. It's clear that insulin is not the only thing that affects BG, yet most of the sciencey pages only talk about it. It seems weird.
No, if the body senses it has insufficient glucose, then it results in cortisol being released to break down muscle tissue and fat to release glucose (gluconeogenesis). Excess, prolonged high cortisol has impact on brain, heart, skin, sleep, etc. The brain primarily runs on glucose as preferential energy source, so we need it http://neuro.hms.harvard.edu/harvar...n-newsletter/and-brain-series/sugar-and-brain
Type 2 diabetes accelerates brain aging,” says Novak, “which, in turn accelerates the progression of functional decline. With intranasal insulin, we’re hoping to find a new avenue for treatment to slow down these effects or prevent them altogether.”
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