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<blockquote data-quote="RuthW" data-source="post: 943670" data-attributes="member: 148713"><p>Well, I am happy to see you can listen to Tim on why he might be wrong about "normal" now, so I'll leave that point.</p><p></p><p>I'll also point out that your definition of "diabetes" leaves a bit to be desired biologically. In my case, and in the case of most Type 1s, it is part of an autoimmune disorder, which has several other elements, the insulin issue being only one of the symptoms of my autoimmune disorder. Certainly it is the part on which people tend to concentrate because it's the part likely to be fatal first. But it's not the only part.</p><p></p><p>I tend to take a wider view of my health and my autoimmune disorder. It's not just all about insulin and blood sugar.</p><p></p><p>So, for example, the micro-focus on insulin tends to leave out the wider genetic aspects of diabetes and its interrelation with other disorders. Her's a very nice example:</p><p></p><p><a href="http://www.ncbi.nlm.nih.gov/pubmed/26209325" target="_blank">http://www.ncbi.nlm.nih.gov/pubmed/26209325</a></p><p></p><p>This relationship was first remarked on in the nineteenth century, in fact.</p><p></p><p>There are other possible factors to take into account. As well as the genetic aspects of immune disorders, there are the environmental "triggers". People tend to assume that gluttony is the "trigger" for Type 2, but in my opinion it is much more likely that, like Type 1 and schizophrenia, the guilty culprit is probably a virus. We get it, it seems to pass, but it triggers the disorder. We know, for example, that you are much more likely to get schizophrenia if you live in a city. Both Type 1 and Type 2 have exploded in the last century, all over the world. From an epidemiological point of view, that suggests that urbanization, and therefore contact with more viruses, etc at least correlates with that spread.</p><p></p><p>So, yes, I'm not particularly convinced of this guy's genius. I think he's missing the main point.</p><p></p><p>And you ask "then if this pattern had always existed, the lifestyle diseases associated with insulin resistance – diabetes, high blood pressure, atherosclerosis, some cancers – shouldn’t have peaked in the twentieth century.)"</p><p></p><p>Well, that would be true if all that had not coincided with the discovery and spread of antibiotics. People who would previously have died young of infectious diseases now survive to die of other things.</p></blockquote><p></p>
[QUOTE="RuthW, post: 943670, member: 148713"] Well, I am happy to see you can listen to Tim on why he might be wrong about "normal" now, so I'll leave that point. I'll also point out that your definition of "diabetes" leaves a bit to be desired biologically. In my case, and in the case of most Type 1s, it is part of an autoimmune disorder, which has several other elements, the insulin issue being only one of the symptoms of my autoimmune disorder. Certainly it is the part on which people tend to concentrate because it's the part likely to be fatal first. But it's not the only part. I tend to take a wider view of my health and my autoimmune disorder. It's not just all about insulin and blood sugar. So, for example, the micro-focus on insulin tends to leave out the wider genetic aspects of diabetes and its interrelation with other disorders. Her's a very nice example: [URL]http://www.ncbi.nlm.nih.gov/pubmed/26209325[/URL] This relationship was first remarked on in the nineteenth century, in fact. There are other possible factors to take into account. As well as the genetic aspects of immune disorders, there are the environmental "triggers". People tend to assume that gluttony is the "trigger" for Type 2, but in my opinion it is much more likely that, like Type 1 and schizophrenia, the guilty culprit is probably a virus. We get it, it seems to pass, but it triggers the disorder. We know, for example, that you are much more likely to get schizophrenia if you live in a city. Both Type 1 and Type 2 have exploded in the last century, all over the world. From an epidemiological point of view, that suggests that urbanization, and therefore contact with more viruses, etc at least correlates with that spread. So, yes, I'm not particularly convinced of this guy's genius. I think he's missing the main point. And you ask "then if this pattern had always existed, the lifestyle diseases associated with insulin resistance – diabetes, high blood pressure, atherosclerosis, some cancers – shouldn’t have peaked in the twentieth century.)" Well, that would be true if all that had not coincided with the discovery and spread of antibiotics. People who would previously have died young of infectious diseases now survive to die of other things. [/QUOTE]
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