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Message: <blockquote data-quote="hanadr" data-source="post: 66405" data-attributes="member: 8110">Most people adapt to Metformin. Some who can't are put on to other medicatio. I have been on Metformin 2 x 500 per day for 5 years. I combine this with a lowered carb diet. I was on gliclazide, but dropped it when my weight was climbing. I lost 18kg and weight loss stopped.I'm trying desperate measures to get more weight off. I'm happy to take Metformin, it seems safe and works on insulin resistance not directly on the pancreas.</blockquote>

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