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Diabetes Discussion
Type 1.5/LADA Diabetes
LADA vs. Type 1?
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<blockquote data-quote="DaftThoughts" data-source="post: 1474205" data-attributes="member: 317436"><p>In broad terms, this is largely correct. Genetically, there are differences between type 1 and LADA so it's not technically correct to say they're identical.</p><p></p><p><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928363/" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928363/</a></p><p><a href="http://www.diabetes.co.uk/news/2017/may/researchers-uncover-genetic-features-of-lada-diabetes-99442364.html" target="_blank">http://www.diabetes.co.uk/news/2017/may/researchers-uncover-genetic-features-of-lada-diabetes-99442364.html</a></p><p></p><p>That's not to say it's not basically type 1 with a different approach (my medical ID bracelets all say T1 in part because it is recognized as a form of T1) but these genetic differences might, one day, indicate a different way of diagnosing, different treatments more tailored to LADA needs etc. It's worth recognizing they're not 100% the same for the future of diabetes treatments.</p><p></p><p></p><p>Probably not, if only because treatment for LADA can be enormously different from the fast onset type 1. There are lots of ways LADA is different as it progresses to full insulin dependency - I would have had no place in the T1 forum at first, I spent several years on oral medication before insulin which is not how T1 is typically treated after all. There are also subtle differences in how the condition expresses itself that don't fully line up with regular T1, enough to warrant a more specialized approach (the extended honeymoon period being one of them).</p></blockquote><p></p>
[QUOTE="DaftThoughts, post: 1474205, member: 317436"] In broad terms, this is largely correct. Genetically, there are differences between type 1 and LADA so it's not technically correct to say they're identical. [URL]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928363/[/URL] [URL]http://www.diabetes.co.uk/news/2017/may/researchers-uncover-genetic-features-of-lada-diabetes-99442364.html[/URL] That's not to say it's not basically type 1 with a different approach (my medical ID bracelets all say T1 in part because it is recognized as a form of T1) but these genetic differences might, one day, indicate a different way of diagnosing, different treatments more tailored to LADA needs etc. It's worth recognizing they're not 100% the same for the future of diabetes treatments. Probably not, if only because treatment for LADA can be enormously different from the fast onset type 1. There are lots of ways LADA is different as it progresses to full insulin dependency - I would have had no place in the T1 forum at first, I spent several years on oral medication before insulin which is not how T1 is typically treated after all. There are also subtle differences in how the condition expresses itself that don't fully line up with regular T1, enough to warrant a more specialized approach (the extended honeymoon period being one of them). [/QUOTE]
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