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<blockquote data-quote="richieh" data-source="post: 150042" data-attributes="member: 21067"><p><strong>Re: LANTUS PROBLEMS</strong></p><p></p><p>What can I say.. I've been a Type 1 Diabetic for 30yrs and have tried pretty much everything out there from an insulin point of view.</p><p></p><p>I was on Lantus and NovoRapid for several years and had all the yo yo effects described.</p><p>Point 1 NovoRapid is not great for people who process carbs quick.... it's peak for me 1 3-4 hours... I'm now on Apidra which peaks at 2-3.</p><p></p><p>Lantus.... it just didn't work, I had the days when you can't get it off the floor and days when you see a 12 , put 2 units of fast acting in, see 11.6 3hrs later put another 2 units of fast acting in... wake up in the morning... 13.... It makes no sense...</p><p></p><p>I'm now on a split levamir dose... I see the issue less, but its still there...the conclusion I have is that its actually a digestive problem... I believe that on certain days your body just decides not to work as effectively as it could... it then drags out the digestive process over 5-6 hours rather than 3-4... this usually ties in with a fealing of indigestion.</p><p></p><p>Be aware that most of these "long acting" insulins are totally dependent on volume injected/weight and location. I had a graph of the absorption rate of Levamir, it shows that a dose of 10 units/70kg burns out in 16hrs.. and location of course... if you put it somewhere in a muscle group which moves a lot, the insulin take up will be quicker, if you're not as active or you put it in an area with little movement, it will take your body longer to fully absorb it.</p></blockquote><p></p>
[QUOTE="richieh, post: 150042, member: 21067"] [b]Re: LANTUS PROBLEMS[/b] What can I say.. I've been a Type 1 Diabetic for 30yrs and have tried pretty much everything out there from an insulin point of view. I was on Lantus and NovoRapid for several years and had all the yo yo effects described. Point 1 NovoRapid is not great for people who process carbs quick.... it's peak for me 1 3-4 hours... I'm now on Apidra which peaks at 2-3. Lantus.... it just didn't work, I had the days when you can't get it off the floor and days when you see a 12 , put 2 units of fast acting in, see 11.6 3hrs later put another 2 units of fast acting in... wake up in the morning... 13.... It makes no sense... I'm now on a split levamir dose... I see the issue less, but its still there...the conclusion I have is that its actually a digestive problem... I believe that on certain days your body just decides not to work as effectively as it could... it then drags out the digestive process over 5-6 hours rather than 3-4... this usually ties in with a fealing of indigestion. Be aware that most of these "long acting" insulins are totally dependent on volume injected/weight and location. I had a graph of the absorption rate of Levamir, it shows that a dose of 10 units/70kg burns out in 16hrs.. and location of course... if you put it somewhere in a muscle group which moves a lot, the insulin take up will be quicker, if you're not as active or you put it in an area with little movement, it will take your body longer to fully absorb it. [/QUOTE]
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