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Message: <blockquote data-quote="tim2000s" data-source="post: 749927" data-attributes="member: 30007">Thanks for that explanation [USER=84861]@Heathenlass[/USER] It very much mirrors my experience of Lantus. I discovered relatively early that it didn't last 24 hours, and switched to splitting my doses to compensate. Has to be said that the Diabetic Clinic didn't really know that much either. Once I started to cycle in to work, I really hit the issues. As my leg muscles improved (and body fat levels on my legs reduced) I started to do my bedtime dose and see a massive variety in the waking blood glucose levels. Eating the same food/drink combinations, I'd wake up with ranges that went from 2.5 to 14.9, for no apparent reason. Similarly to you, no-one on the diabetic clinic side really seemed to know anything, and I didn't understand what i was doing wrong, as I couldn't see any pattern to these massive variances. It was only last year, when I had the collapsing hypo in the middle of St Swithin's Lane that I could identify that there was a problem with Lantus. I'd eaten nothing, injected my normal morning dose, and here I was all of a sudden with a crashing hypo that knocked me down (and believe me this was the first time I've had a hypo that has had that effect, so I really wasn't happy). And the only insulin that could have done it was the Lantus. That's what brought the question up here and created this thread.What's also very noticeable is that the bg level swings that I experienced quite a lot with Lantus aren't happening to anywhere near the same extent on Levemir. While three weeks isn't a huge amount of time to pass judgement, there does seem to be more predictability in Levemir, and I am able to push up and down with more alacrity. The pace of change is noticeably slower.I am surprised that there has been no MHRA report on Lantus, because as far as I can see from the fairly large number of cases reported and that certain health authorities have stopped prescribing it, it doesn't seem to be fit for purpose. You shouldn't need to use an insulin to discover that it will nearly kill you or wreck your control due to the way it has been designed.</blockquote>

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