I've travelled a lot with Humalin I and Humalog (Central & South America, Morocco, all over Europe etc for up to 4.5 months in South America) and never bothered with a Frio pouch. Never stayed in rooms with fridges, either, although have often found fridges in cafes, restaurants, hotel / hostel kitchens etc where I can leave insulin (speaking Spanish in Latin America is vital for this!) I used a stainless steel thermos flask for main stock of insulin, and relied on shade / wrapping in bag to keep "daily" insulin cool.