Liraglutide reduces heart attack risk in type 2 diabetes

[DCUK NewsBot]

A common type 2 diabetes drug has been found to lower the risk of heart attack, stroke and cardiovascular death, researchers have said. Liraglutide (marketed as Victoza and Saxenda) is a GLP-1 analogue drug that is used to help people to lower their blood glucose levels. Last year, Victoza received EU approval to treat cardiovascular risks in type 2 diabetes. Previous research has shown that the drug reduces the risk of a major heart attack or stroke among those with diabetes, who were already suffering from established cardiovascular disease. Because cardiovascular disease is more likely among people with diabetes, Karolinska Institutet researchers in Sweden wanted to investigate whether the drug could reduce the risk of serious cardiovascular events in a more general population of people with diabetes that included those with or without a history of cardiovascular disease. The trial involved 46,000 people with type 2 diabetes, half of whom were given liraglutide, the others took medication from the diabetes drug class DPP-4 inhibitors. The findings showed there were 14 major cardiovascular events per 1,000 people in the liraglutide group, while the DPP-4 inhibitor group saw 15.4 per 1,000. Björn Pasternak, senior researcher at the Department of Medicine, Solna, Karolinska Institutet, and affiliated with Statens Serum Institut, said: "Our study provides support for the cardiovascular effectiveness of liraglutide among a broader unselected group of patients, providing important confirmatory evidence from routine clinical practice. "We believe it may be of interest to drug regulators, clinical guidelines, physicians, and patients." The findings of the study have been published in the Lancet Diabetes &Endocrinology journal.

Continue reading...

 

[bulkbiker]

In other words controlling and reducing hyperinsulinaemia..which we all know is a primary cause of CVD lowers the risk. No drugs needed if dietary modifications are effective.

 

[ickihun]

Good news for many who need Victoza.
Have you seen this @ally1?
Its very reassuring.

 

[ickihun]

In other words controlling and reducing hyperinsulinaemia..which we all know is a primary cause of CVD lowers the risk. No drugs needed if dietary modifications are effective.

I didn't know hypers cause CVD?
Many type1s who have brittle diabetes and suffer more with hypos from insulin injections suffer with CVD and associated problems.

 

[bulkbiker]

I didn't know hypers cause CVD?
Many type1s who have brittle diabetes and suffer more with hypos from insulin injections suffer with CVD and associated problems.

More likely they have the hypos because they are eating too many carbs and over correcting with insulin.. although far be it from me to advise any Type 1s's on what to eat... ever..
But it may seem like they are giving themselves hyperinsulinaemia?

Note I am talking about hyperinsulinaemia and not hyperglycemia.

 

[ickihun]

More likely they have the hypos because they are eating too many carbs and over correcting with insulin.. although far be it from me to advise any Type 1s's on what to eat... ever..
But it may seem like they are giving themselves hyperinsulinaemia?

Note I am talking about hyperinsulinaemia and not hyperglycemia.

Thanks @bulkbiker. I knew but I just wanted it pointed out. As it does help.