I have been taking Targin 20/10 which is Naltrexone and oxycodone. I take it for severe disabling pain not related to my diabetes. I have damage to my neck shoulder, elbow and arm.
I also take Tramadol xr and Tramadol as well as Codralgyn (paradol and codeine combo)
I have done the round of a lot of different pain killers. Oxycodone did not work on its own for me in that it had very little effect.
I can now function on the whole. I still have days of pain but I do not have some of the extreme effects I had with other meds.
The biggest side effect is constipation, which doesnt help also low carbing. I make sure I drink plenty of water and use chia seeds a lot as I hate taking movicol which is my prescribed med for constipation.