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Lyumjev v Novorapid

Jc3131

Well-Known Member
Messages
329
Type of diabetes
Type 1
Treatment type
Insulin
Hello everyone.

Has anyone has had any issues changing from Novorapid to Lyumjev?

My hba1c while using novorapid was 48 and I asked if I could be changed to a quicker insulin as it was taking up to an hour for the insulin to work ( not always, but a lot of the time).

Fast forward 2-3 months, and my hba1c is rising, and at the moment, it's 54. My levels are all over the place, and I just can't seem to get things as steady(ish) as I used to.

I know that Lyumjev starts working a bit quicker, but I seem to be taking a lot more of it to get levels down. I'm having higher peaks with it as well. I have also upped my Lantus to help counteract taking more insulin than normal, and it's still not helping get it under control.

Add quite a few dodgy Libre sensors in the mix, and it's becoming a bit of a nightmare. This is the most I've struggled since I was diagnosed 7.5 years ago.

I'm thinking of going back to Novorapid. I've also noticed I have more bruising using Lyumjev than I did when I used Novorapid.

Cheers in advance for any info.
 
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I do find that Lyumjev is more stubborn with highs and takes longer to bring me down if I am running higher (Above 10 for me usually).

I am also on an insulin pump, so I am constantly being drip-fed Lyumjev as opposed to having a basal/bolus regime. Contrary to belief, as I learnt, although Lyumjev does work quicker, it isn't necessarily always going to start working instantly, and I still have to pre-bolus for meals by around 10-15 minutes.

Lyumjev is known to make sites more sore and cause redness/bruising. I believe whatever makes it work quicker causes these reactions.

If you've tried everything possible and it still isn't working for you, there's no harm in going back to Novorapid. There is also Fiasp, which could be an option to try. It works similarly to Lyumjev but is made by Novo Nordisk, which makes Novorapid.
 
I switched from Novorapid to Ljumjev around 5 months ago, Novo was taking too long to work and my time in range was around 60-65%, since switching to Ljumjev I have got my TIR to 85%, however my HbA1c hasn't improved and sits around 52 but as TIR is considered the standard to aim for in regards to control, this is according to my DSN who states it's more important to be achieving a better TIR due to stability and less hypos.

Things i've learned, it stings due to the preservatives so sites can become painful and lumpy, in my case they also bleed so I have to change regularly (on pump with steel sets), it does work quicker yes so can reduce highs, but if I go high it takes some doing to get back down again, last night was an example, had pizza, only 2 small slices but hit 17 and took till 1am to come back down again, I normally have to hit the gym when levels are up to get them down as I prefer to chase highs with exercise, however last night unsure if it was due to my site being lumpy, bleeding and sore so changed my set. I feel that it does start working within 5 mins, anytime I try to pre-bolus for longer I find I start heading south.

As Fairy has said try doing basal testing first, this is where I would start to check it's dosage is right first before looking at the quick acting insulin,
 
Was using NovoRapid for 25+ years, switched to Fiasp (Novorapid with stuff in) and worked great for a few weeks, then became resistant.

Switched to Lyumjev - worked great, then same issue.

In the end I changed my cannula (9mm seemed to work better for me) and moved away from over-used sites. Worked much better and more consistent.

After 6 months, became resistant to Lyumjev, so switched to Fiasp again (now on 9mm cannula and moving sites regularly) and it works well - still not great at brining down highs above 14 - but tolerable as below that most of the time.

Might be worth trying new injection sites, and if that still gives no joy - try Fiasp - Ultrafast makes life easier if you can find the right solution.
 
Thanks for the replies.

I haven't done a basal test as I always seem to be at work, so I didn't want to do it while working.

The good news is that I have sort of got my control back to where I had it with Novorapid. I take 1 more unit of lyumjev than I would have Novorapid, and I seem to be in range more.

I am taking 13 u of Lantus instead of 12 and that seems to have helped as well.

I've started to take the insulin in my thigh to give stomach a break, this has stopped the stinging.

I've cut Lager out for now, which sometimes spikes me, but I was the same using novorapid, so I knew that alcohol was an issue, esp the lagers I like.
 
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