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Message: <blockquote data-quote="Vectian" data-source="post: 2756159" data-attributes="member: 588965">The entire point of that paper and the massive amount of research and studies it pools was to show the causality which was not conclusively shown before. It's all there if you read it! Even in the summary:Aims: To appraise the clinical and genetic evidence that low-density lipoproteins (LDLs) cause atherosclerotic cardiovascular disease (ASCVD). Conclusion: Consistent evidence from numerous and multiple different types of clinical and genetic studies unequivocally establishes that LDL causes ASCVD.</blockquote>