One baby I had on metformin and insulin throughout the whole process who hasn't a weight problem. My first on insulin only as they wanted me to trial metformin in pregnancy but I refused after waiting decades to get pregnant (mind you... on metformin)... he has a weight issue but my GP has refused us metformin as his hba1c is perfect. He's involved in research on genes and leptin resistance.
I feel this research above isn't targeting genes. Just the 'obesity in pregnancy' effects and probability of creating another metabolic disorder evolution.
Yes, we are evolving into diabetics. Irrespective of the predisposition or not?
Is the next step to refuse fertility aid to obese patients? The nhs already does. My sister and hundreds more are forced to pay private and often into debt to have even their first sign of a pregnancy. Even if that pregnancy isn't successful.
I was lucky that the professor agreed my 15.5st underactive thyroid obese body was allowed for St.Thomas's, London part paid funding for my unsuccessful IVF. If only I knew I only needed longterm metformin treatment. Then.
2 successful babies on metformin therapy and.... hopefully one day grandchildren, whose IR I can understand, I'd like to think.
Obesity due to IR and conceiving can be much better managed and understood. Now.
Going forward all patients with IR should get help to stop obesity causing health problems, not just young women wishing to conceive. All IR patients can end up with dangerous untreated metabolic disease. Mind you even the none obese type2s.
Obesity doesn't guarantee early death for everyone.