I have been taking slow release Metformin since about 18 months after I was diagnosed nearly 20 years ago without issues but some years ago my doctor added Sitagliptin and I now have Bullous pemphigoid antibodies an inflammatory condition where the body’s immune system attacks the skin. I have only recently discovered that there may be a link between Sitagliptin and pemphigoid. I was put on prednisolone initially so there went my glucose control, then I was reduced on them, gradually stopping, and put on Azathioprine which suppresses the immune system. I was doing well until July this year and it flared up again, worse than ever. It is the most horrible thing ever, my whole body from knees to shoulders constantly itches. am seeing my GP on Wednesday and the Dermatologist on 12th of this month. In the meantime I have stopped taking the Sitagliptin. I am going to ask GP about liraglutide. Tessa11’s experience with the aches and pains sounds like Polymyalgia which I had before the BPA’s. I was put on prednisolone for that, and it went into remission and the BPA flare up came just after I came off the steroids so they put me straight back on them. My niece who is T2 on insulin and Metformin has just been diagnosed with lupus, and my understanding is that these conditions together with Crohn’s disease and rheumatoid arthritis are all somehow related.