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Metformin - Benefits of low dose compared to stopping
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<blockquote data-quote="AloeSvea" data-source="post: 1986134" data-attributes="member: 150927"><p><span style="font-family: 'Arial'">[USER=500292]@FSnow[/USER], I think your question is a really good question. I still ask myself the same question four and a half years after my own diagnosis, and I <em>still </em>don't have a definitive answer! </span></p><p><span style="font-family: 'Arial'"></span></p><p><span style="font-family: 'Arial'">The pros and the cons come out to look pretty even to me in the 'to take metformin or not to take metformin' question. (In the context of going low-carb of course! For me low-carbing is the default position... ie is "of course".) Because in my life previously I have leaned on the side of not going the trad medical route I have gone to the side of not medicating. A deep suspicion of pharmacology I have not been able to shake. (Thalidomide, HRT, statins... these are what I think of when having this discussion with myself.) </span></p><p><span style="font-family: 'Arial'"></span></p><p><span style="font-family: 'Arial'">But metformin has a great safety record, and it gets a pretty good result. Not as good as going low-carb, is my understanding, but still - it can lower your HBA1c by enough digits (or percentage points if going USA) to make it worthwhile. And definitely if you are reading Jenny Ruhl, and want to be part of the 5.0-club for better health with diabetes. (Hers is the most compelling argument that I have read, and the one I really consider when pondering on your question.) I think she has this great image of our cells bathing in a toxic glucose bath, or was that someone else? But an image that can spur one to the metformin bottle for sure! (IUnless digestive side effects and possible nutritional deficiencies drive you to close the bottle again?)</span></p><p><span style="font-family: 'Arial'"></span></p><p><span style="font-family: 'Arial'">And, But, again, the ACCORD study et al seems to be saying, if I have understood correctly, that getting your BG down as low as it can go with pharmaceuticals, at a certain level at least - I think the American figure is below 7.0%? Or maybe 6.5%? (Please anyone jump in and correct me if I am wrong, as I am operating on memory here) does not actually save you from a too early death from cardiovascular disease and so on - a big issue for us with blood glucose dysregulation and high insulin levels etc etc. </span></p><p><span style="font-family: 'Arial'"></span></p><p><span style="font-family: 'Arial'">Pros and cons, pros and cons.</span></p><p><span style="font-family: 'Arial'"></span></p><p><span style="font-family: 'Arial'">I have probably not helped you at all, and I am sorry for this. But I thought that by sharing with you my own ponderings on this issue might help you on your own path to better health. Make the decision making clearer at least? To know what is on the pros side, and what on the con. And you can look at your own balance sheet to help you make the decision.</span></p></blockquote><p></p>
[QUOTE="AloeSvea, post: 1986134, member: 150927"] [FONT=Arial][USER=500292]@FSnow[/USER], I think your question is a really good question. I still ask myself the same question four and a half years after my own diagnosis, and I [I]still [/I]don't have a definitive answer! The pros and the cons come out to look pretty even to me in the 'to take metformin or not to take metformin' question. (In the context of going low-carb of course! For me low-carbing is the default position... ie is "of course".) Because in my life previously I have leaned on the side of not going the trad medical route I have gone to the side of not medicating. A deep suspicion of pharmacology I have not been able to shake. (Thalidomide, HRT, statins... these are what I think of when having this discussion with myself.) But metformin has a great safety record, and it gets a pretty good result. Not as good as going low-carb, is my understanding, but still - it can lower your HBA1c by enough digits (or percentage points if going USA) to make it worthwhile. And definitely if you are reading Jenny Ruhl, and want to be part of the 5.0-club for better health with diabetes. (Hers is the most compelling argument that I have read, and the one I really consider when pondering on your question.) I think she has this great image of our cells bathing in a toxic glucose bath, or was that someone else? But an image that can spur one to the metformin bottle for sure! (IUnless digestive side effects and possible nutritional deficiencies drive you to close the bottle again?) And, But, again, the ACCORD study et al seems to be saying, if I have understood correctly, that getting your BG down as low as it can go with pharmaceuticals, at a certain level at least - I think the American figure is below 7.0%? Or maybe 6.5%? (Please anyone jump in and correct me if I am wrong, as I am operating on memory here) does not actually save you from a too early death from cardiovascular disease and so on - a big issue for us with blood glucose dysregulation and high insulin levels etc etc. Pros and cons, pros and cons. I have probably not helped you at all, and I am sorry for this. But I thought that by sharing with you my own ponderings on this issue might help you on your own path to better health. Make the decision making clearer at least? To know what is on the pros side, and what on the con. And you can look at your own balance sheet to help you make the decision.[/FONT] [/QUOTE]
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