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<blockquote data-quote="Emck" data-source="post: 2631897" data-attributes="member: 498565"><p>Hi all,</p><p></p><p>I am currently taking SR metformin to manage insulin resistance in pregnancy (I am type 1). </p><p></p><p>I’m currently 29 weeks and have hit another resistance spike. My endocrinologist has advised that I can increase my metformin dose to help with this. </p><p></p><p>I have been taking 2x500mg tablets in the evening (as advised by endo) and they really helped to bring down insulin requirements for around 10 weeks. </p><p></p><p>I have been trying to introduce a third 500mg tablet but I’m not sure when the best time to take it is. With the 2 evening tablets, I have had zero side effects. This I added starting taking the extra 500mg tablet in the morning and the side effects have been bad. I’ve been so nauseous and having very painful stomach cramps. </p><p></p><p>Does anyone know if I can take 3x 500mg Metformin SR tablets at the same time, or if a dose that size needs to be split up?</p><p></p><p>Multiple endocrinologists have all given me different answers on this. Some say it shouldn’t matter as it’s slow release and others saying to split the dose.</p></blockquote><p></p>
[QUOTE="Emck, post: 2631897, member: 498565"] Hi all, I am currently taking SR metformin to manage insulin resistance in pregnancy (I am type 1). I’m currently 29 weeks and have hit another resistance spike. My endocrinologist has advised that I can increase my metformin dose to help with this. I have been taking 2x500mg tablets in the evening (as advised by endo) and they really helped to bring down insulin requirements for around 10 weeks. I have been trying to introduce a third 500mg tablet but I’m not sure when the best time to take it is. With the 2 evening tablets, I have had zero side effects. This I added starting taking the extra 500mg tablet in the morning and the side effects have been bad. I’ve been so nauseous and having very painful stomach cramps. Does anyone know if I can take 3x 500mg Metformin SR tablets at the same time, or if a dose that size needs to be split up? Multiple endocrinologists have all given me different answers on this. Some say it shouldn’t matter as it’s slow release and others saying to split the dose. [/QUOTE]
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