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Metformin. how soon does it show effect on hba1c?
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<blockquote data-quote="Freema" data-source="post: 1328342" data-attributes="member: 329519"><p>somebody in here send me a link as I questioned the effect of metformin, if it was worth taking at all.. and I was convinced to continue from his argumantation and the numbers given in a link there, I´ll try to</p><p></p><p>find...<a href="http://www.diabetes.co.uk/forum/threads/how-much-does-metformin-actually-help.111894/" target="_blank">http://www.diabetes.co.uk/forum/threads/how-much-does-metformin-actually-help.111894/</a></p><p></p><p>but yes it doen´t help everybody the same, and many do not get the maximum dose... and so on like it is with most druggs anyway.. we are not identical maschines and a lot of medicine doen´t work the same in different gene/ethnic variaties either...</p><p>also there cound be differences form one sex to the other and from young persons to older.</p><p></p><p>But I have trouble understanding these percentage numbers and ways to calculate if looked on the Daily average blood glucose a lowering of a HbA1b from 7.8 till 5.6 is Said to be a maybe 5% lowering But is it actually not a much higher percentage it has been lowered with if</p><p>7.8 = 100% How many percentage has it been lowered to become 5.6 instead about a third I would say ? A third is 30% I did ask and look for a graph that could show this but wasn't able to find any ilustrations of the effect put into a graph anywhere in the web..</p><p></p><p>here is an article on metformins effectiveness, it says :</p><p></p><p>Metformin lowers fasting blood glucose levels by an average of 25% (17 to 37%), postprandial blood glucose up to 44.5%, and the A1c by an average of 1.5% (0.8 to 3.1%). Metformin reduces raised plasma insulin levels in cases of metabolic syndrome by as much as 30% and reduces the need for injected insulin in Type 2s by 15 to 32%.<a href="http://www.diabetesnet.com/about-diabetes/diabetes-medications/metformin" target="_blank">http://www.diabetesnet.com/about-diabetes/diabetes-medications/metformin</a></p><p></p><p></p><p></p><p>guess that is where I got some of the numbers from</p></blockquote><p></p>
[QUOTE="Freema, post: 1328342, member: 329519"] somebody in here send me a link as I questioned the effect of metformin, if it was worth taking at all.. and I was convinced to continue from his argumantation and the numbers given in a link there, I´ll try to find...[URL]http://www.diabetes.co.uk/forum/threads/how-much-does-metformin-actually-help.111894/[/URL] but yes it doen´t help everybody the same, and many do not get the maximum dose... and so on like it is with most druggs anyway.. we are not identical maschines and a lot of medicine doen´t work the same in different gene/ethnic variaties either... also there cound be differences form one sex to the other and from young persons to older. But I have trouble understanding these percentage numbers and ways to calculate if looked on the Daily average blood glucose a lowering of a HbA1b from 7.8 till 5.6 is Said to be a maybe 5% lowering But is it actually not a much higher percentage it has been lowered with if 7.8 = 100% How many percentage has it been lowered to become 5.6 instead about a third I would say ? A third is 30% I did ask and look for a graph that could show this but wasn't able to find any ilustrations of the effect put into a graph anywhere in the web.. here is an article on metformins effectiveness, it says : Metformin lowers fasting blood glucose levels by an average of 25% (17 to 37%), postprandial blood glucose up to 44.5%, and the A1c by an average of 1.5% (0.8 to 3.1%). Metformin reduces raised plasma insulin levels in cases of metabolic syndrome by as much as 30% and reduces the need for injected insulin in Type 2s by 15 to 32%.[URL]http://www.diabetesnet.com/about-diabetes/diabetes-medications/metformin[/URL] guess that is where I got some of the numbers from [/QUOTE]
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