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Diabetes Management
Diabetes Medication and Drugs
Metformin/Biguanides
Metformin Vs Gliclazide or others??
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<blockquote data-quote="Daibell" data-source="post: 313709" data-attributes="member: 21149"><p>Hi. It's not for me to try to be the GP, but my understanding is:</p><p></p><p>Metformin SR does suit most people stomach wise, but sadly it doesn't suit your friend but may suit you. Met is optimal for T2's who are overweight with insulin resistance. Gliclazide works by stimulating the pancreas and is the more preferred option for those of normal weight. Then there is Sitagliptin which works by suppressing an ezyme that in turn suppresses the pancreas producing insulin a certain time after meals. I'm on all three tablets! Gliclazide can cause hypos if your pancreas still has enough cells left and can cause some weight gain. Sitagliptin is neutral ref weight gain and can't cause hypos; it's the most expensive and newest drug of the three. As you may be aware the first thing to do with T2 is always to get the diet right thru reducing carbs then go on to medication. Which medication depends on your T2 causes and there are no real tests to separate out the causes so it really is trial and error</p></blockquote><p></p>
[QUOTE="Daibell, post: 313709, member: 21149"] Hi. It's not for me to try to be the GP, but my understanding is: Metformin SR does suit most people stomach wise, but sadly it doesn't suit your friend but may suit you. Met is optimal for T2's who are overweight with insulin resistance. Gliclazide works by stimulating the pancreas and is the more preferred option for those of normal weight. Then there is Sitagliptin which works by suppressing an ezyme that in turn suppresses the pancreas producing insulin a certain time after meals. I'm on all three tablets! Gliclazide can cause hypos if your pancreas still has enough cells left and can cause some weight gain. Sitagliptin is neutral ref weight gain and can't cause hypos; it's the most expensive and newest drug of the three. As you may be aware the first thing to do with T2 is always to get the diet right thru reducing carbs then go on to medication. Which medication depends on your T2 causes and there are no real tests to separate out the causes so it really is trial and error [/QUOTE]
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