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Message: <blockquote data-quote="Antje77" data-source="post: 2749546" data-attributes="member: 372207">May I ask how your brother was diagnosed with this? I'm sometimes frustrated with what I think is insulin resistance (but not sure about that). The liver produces glucose all day anyway, regardless of BG, that's why we need basal insulin.As for lipids, mine were all out of whack upon diagnosis, but they settled nicely in the green when my BG normalised.Is there a particular reason why your brother can'tget his BG down with insulin? For most, metformin doesn't make that much of a difference although it does for some. And I think anyone with serious side effects from a medication should be looking at other possibilities than upping the meds, pooping your pants in public simply isn't fun. And there are lots of medications to try.</blockquote>

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