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metformine when low calories under 1000cals
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<blockquote data-quote="DavidGrahamJones" data-source="post: 1255527" data-attributes="member: 245335"><p>Wiki says: "<em>The drug's main effect is to decrease hepatic glucose production". </em>Maybe on a low calorie or low carb diet your glucose production is low and Metformin makes it worse. Lactic Acidosis is a known side effect and although many will have had Lactic Acidosis to some degree (muscle pain after strenuous exercise that you wouldn't normally do) it's rarely serious.</p><p></p><p>I am presently on very low calories and the only change I have noticed is a return to the bad old days of the runs. Some muscle pain but not like the muscle pain after strenuous exercise.</p></blockquote><p></p>
[QUOTE="DavidGrahamJones, post: 1255527, member: 245335"] Wiki says: "[I]The drug's main effect is to decrease hepatic glucose production". [/I]Maybe on a low calorie or low carb diet your glucose production is low and Metformin makes it worse. Lactic Acidosis is a known side effect and although many will have had Lactic Acidosis to some degree (muscle pain after strenuous exercise that you wouldn't normally do) it's rarely serious. I am presently on very low calories and the only change I have noticed is a return to the bad old days of the runs. Some muscle pain but not like the muscle pain after strenuous exercise. [/QUOTE]
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