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MODA - Mature Onset Diabetes in Adults
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<blockquote data-quote="efaitch" data-source="post: 26273" data-attributes="member: 7899"><p>Never heard of MODA, but MODY is like Hana has said maturity onset diabetes of the young. Maturity onset diabetes in Adults is just that, diabetes in adulthood.</p><p></p><p>LADA is Latent autoimmune diabetes in adulthood - which is, simplistically put, type I developed during adulthood (it usually happens in adulthood).</p><p></p><p>MODY is usually diagnosed before the age of 25. There are at least six known types of MODY (or monogenetic diabetes) which are known to exist (and more suspected). MODY is sometimes mistaken for type I <em>or</em> type II diabetes dependent on age of diagnosis and symptoms.</p><p></p><p>Basically, type I diabetes is usually due to an autoimmune reaction whereby the beta cells of the islets of langerhans in the pancreas are attacked by the own body. Type II diabetes - the beta cells still produce insulin, however, there can be some degree of insulin resistance (bodily cells don't accept the insulin) and the production for whatever reason has been compromised (usually polygenic = more than one gene that causes it).</p><p></p><p>So, the question is. Are you producing any insulin at all? With the BG levels that you've recorded, it's more than likely that you are - and it's most likely that you've developed type II diabetes.</p><p></p><p>With regards to classification of diabetes, there seems to be a lot of confusion over what type people have. Type 1.5 is a term that is used for LADA or MODY. However, a more correct term of usage would be insulin dependent diabetes mellitus (IDDM) or non-insulin dependent diabetes mellitus (NIDDM).</p><p></p><p>In your case, you've been diagnosed with NIDDM (without a test to check for an autoimmune reaction).</p><p></p><p>And, you've already said that you've experienced hypos - without medication for diabetes, this would be a <em>very</em> rare occurance.</p><p></p><p>Hypoglycaemia is caused when your insulin/glucagon feedback mechanism is disturbed.</p><p></p><p>Basically, insulin reduces BG levels. Glucagon is the opposite and acts to convert stored glycogen in the liver to glucose which is released into the blood stream.</p><p></p><p>So, in a non-diabetic (or NIDDM diabetic to a certain extent), insulin will be released when there is too much glucose, then the glucagon mechanism will be activated to combat hypoglycaemia.</p><p></p><p>In most people, including IDDM diabetics, the glucagon mechanism still functions, it's just a balancing act on how much insulin is taken.</p><p></p><p>So, unless on a hypoglycaemic causing agent, as you can see, it's very, very unlikely that you'd have a hypo.</p><p></p><p>It's more likely that the fogginess you experienced is due to high glucose levels.</p><p></p><p>Sorry for the essay!</p><p></p><p>Fiona</p></blockquote><p></p>
[QUOTE="efaitch, post: 26273, member: 7899"] Never heard of MODA, but MODY is like Hana has said maturity onset diabetes of the young. Maturity onset diabetes in Adults is just that, diabetes in adulthood. LADA is Latent autoimmune diabetes in adulthood - which is, simplistically put, type I developed during adulthood (it usually happens in adulthood). MODY is usually diagnosed before the age of 25. There are at least six known types of MODY (or monogenetic diabetes) which are known to exist (and more suspected). MODY is sometimes mistaken for type I [i]or[/i] type II diabetes dependent on age of diagnosis and symptoms. Basically, type I diabetes is usually due to an autoimmune reaction whereby the beta cells of the islets of langerhans in the pancreas are attacked by the own body. Type II diabetes - the beta cells still produce insulin, however, there can be some degree of insulin resistance (bodily cells don't accept the insulin) and the production for whatever reason has been compromised (usually polygenic = more than one gene that causes it). So, the question is. Are you producing any insulin at all? With the BG levels that you've recorded, it's more than likely that you are - and it's most likely that you've developed type II diabetes. With regards to classification of diabetes, there seems to be a lot of confusion over what type people have. Type 1.5 is a term that is used for LADA or MODY. However, a more correct term of usage would be insulin dependent diabetes mellitus (IDDM) or non-insulin dependent diabetes mellitus (NIDDM). In your case, you've been diagnosed with NIDDM (without a test to check for an autoimmune reaction). And, you've already said that you've experienced hypos - without medication for diabetes, this would be a [i]very[/i] rare occurance. Hypoglycaemia is caused when your insulin/glucagon feedback mechanism is disturbed. Basically, insulin reduces BG levels. Glucagon is the opposite and acts to convert stored glycogen in the liver to glucose which is released into the blood stream. So, in a non-diabetic (or NIDDM diabetic to a certain extent), insulin will be released when there is too much glucose, then the glucagon mechanism will be activated to combat hypoglycaemia. In most people, including IDDM diabetics, the glucagon mechanism still functions, it's just a balancing act on how much insulin is taken. So, unless on a hypoglycaemic causing agent, as you can see, it's very, very unlikely that you'd have a hypo. It's more likely that the fogginess you experienced is due to high glucose levels. Sorry for the essay! Fiona [/QUOTE]
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