Found this item about work at Children's Hospital Boston who have identified a new strategy for treating type 2 - it's about a cellular pathway that fails when people become obese so they activate this pathway artificially.
http://www.eurekalert.org/pub_releases/2010-03/chb-ans032610.php
http://www.eurekalert.org/pub_releases/2010-03/chb-ans032610.php