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<blockquote data-quote="DCUKMod" data-source="post: 2203134" data-attributes="member: 345386"><p>As I understand it, there is no upper limit to Levothyroxine. The average adult maintenance dose is 100-200mcgr, so quite a wide span, although up to 300 isn't unknown. (Various sour spices for that information fro my the BNF, MIMS, Thyroid UK etc.). Doses over 200mcgr often lead to a specialist referral.</p><p></p><p>The thing is, the hormone T4 is a passive hormone, and works by being converted to the more active T3. Some folks aren't too good a thread that conversion (including me), so need a bit of help by taking T3 directly. Unless FT3 is being measured, there is now way to know if the T4 in the blood is actually doing anything.</p><p></p><p>If your GP will not test T3, and indeed, sometimes they'd can't request it, but if your FT4 is in range, they don't do the test (grrrrr), the name private tests are available. Medichecks, Thriva, Blue Horizon and MonitorMyHealth all provide variants on the tests, from £29 up to about £100, depending on how deep you want or need to dive.</p><p></p><p>Just a thought.</p></blockquote><p></p>
[QUOTE="DCUKMod, post: 2203134, member: 345386"] As I understand it, there is no upper limit to Levothyroxine. The average adult maintenance dose is 100-200mcgr, so quite a wide span, although up to 300 isn't unknown. (Various sour spices for that information fro my the BNF, MIMS, Thyroid UK etc.). Doses over 200mcgr often lead to a specialist referral. The thing is, the hormone T4 is a passive hormone, and works by being converted to the more active T3. Some folks aren't too good a thread that conversion (including me), so need a bit of help by taking T3 directly. Unless FT3 is being measured, there is now way to know if the T4 in the blood is actually doing anything. If your GP will not test T3, and indeed, sometimes they'd can't request it, but if your FT4 is in range, they don't do the test (grrrrr), the name private tests are available. Medichecks, Thriva, Blue Horizon and MonitorMyHealth all provide variants on the tests, from £29 up to about £100, depending on how deep you want or need to dive. Just a thought. [/QUOTE]
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