Hi and welcome. We can't diagnose here, and we shouldn't even try, but I hope this is helpful -
T2 Diabetes can be diagnosed in a number of ways:
-HBA1c equal to or greater than 48mmol/mol (or 6.5%)
-A random plasma glucose level equal to or greater than 11.1 mmol/litre in someone with typical symptoms of diabetes
-A fasting plasma glucose level equal to or greater than 7.0 mmol/litre
-A plasma glucose level equal to or greater than 11.1 mmol/litre 2 hrs after a 75g load of glucose given by mouth (the Oral Glucose Tolereance Test - OGTT)
(taken from Bilous and Donnelly's Handbook of Diabetes)
Most people these days seem to be diagnosed via HbA1c. Do you know what your last HbA1c was?
There's nothing particularly unusual about a reading of 7.0mmol/l. It's within normal range albeit towards the higher end. If you have an enthusiatic liver it may be topping up your blood glucose levels from its own stores, because it has got used to you running with higher levels. This is very often seen first thing in the morning - the "dawn phenomenon" effect. 16 hours without eating probably isn't enough to totally deplete your liver's glucose stores.
I'm not seeing a spike on your graph. There's a small rise from 7ish to just over 9 (lunch?) and (importantly) a fairly quick fall, and a further similar rise and quick fall around 6. If you ate around those times then that's what you would expect to see - a rise as the carb in the food is digested to glucose and passes into the bloodstream, and a fall as your insulin deals with it.
Rise and fall in blood glucose in response to food etc. is perfectly normal, as you will have seen from your CGM.
Thanks for replying. My last hbAlc was 38. It isn’t the spike after eating me that concerns me, I expect that, it is that my levels are around 7 all night despite me having eaten last at 7pm the night before and me not eating again (on that occasion) until 1pm, hence the spike that followed.Hi and welcome. We can't diagnose here, and we shouldn't even try, but I hope this is helpful -
T2 Diabetes can be diagnosed in a number of ways:
-HBA1c equal to or greater than 48mmol/mol (or 6.5%)
-A random plasma glucose level equal to or greater than 11.1 mmol/litre in someone with typical symptoms of diabetes
-A fasting plasma glucose level equal to or greater than 7.0 mmol/litre
-A plasma glucose level equal to or greater than 11.1 mmol/litre 2 hrs after a 75g load of glucose given by mouth (the Oral Glucose Tolereance Test - OGTT)
(taken from Bilous and Donnelly's Handbook of Diabetes)
Most people these days seem to be diagnosed via HbA1c. Do you know what your last HbA1c was?
There's nothing particularly unusual about a reading of 7.0mmol/l. It's within normal range albeit towards the higher end. If you have an enthusiatic liver it may be topping up your blood glucose levels from its own stores, because it has got used to you running with higher levels. This is very often seen first thing in the morning - the "dawn phenomenon" effect. 16 hours without eating probably isn't enough to totally deplete your liver's glucose stores.
I'm not seeing a spike on your graph. There's a small rise from 7ish to just over 9 (lunch?) and (importantly) a fairly quick fall, and a further similar rise and quick fall around 6. If you ate around those times then that's what you would expect to see - a rise as the carb in the food is digested to glucose and passes into the bloodstream, and a fall as your insulin deals with it.
Rise and fall in blood glucose in response to food etc. is perfectly normal, as you will have seen from your CGM.
Thanks, next time I put one on I will finger prick too to see the variability. I suspect doctors will say they aren’t reliable either. When I was first I’ll I used finger pricks sometimes my blood glucose was as low as 1.6 (I was very I’ll at the time) GP’s just dismissed it. I don’t want to be diagnosed type 2, however i equally don’t want something harming my body undiagnosed. I don’t understand why my GP thinks 11 is the criteria when NICE says 7 fasting. It doesn’t make sense to me.Bear in mind that Libre is not that accurate for some people. You are seeing 7.0 but with an accuracy tolerance of 15%, this could be less than 6.0.
The Libre is great for seeing variations but without a finger prick to judge the accuracy of a sensor, it could be further out for you.
I understand from the Handbook that screening for diabetes via fasting plasma glucose does not capture exactly the same population as those diagnosed by HbA1c or OGTT (I don't know (personally) of anyone who was diagnosed via a FPG test).Thanks for replying. My last hbAlc was 38. It isn’t the spike after eating me that concerns me, I expect that, it is that my levels are around 7 all night despite me having eaten last at 7pm the night before and me not eating again (on that occasion) until 1pm, hence the spike that followed.
Why does the guideline say a fasting blood of 7 if that is in fact normal? I thought they counted fasting as 12 to 14 hours for that? How does the liver play into this, i would be interested to understand more. As I have M.E and also a NAFL which started with my M.E 12 years ago and I have also been hypothyroid since 1994, so have lots of other systems which don’t function very well.
I also intermittently fast, couldn’t that fact distort my hbAlc compared to someone eating in a window of more than 8 hours a day?
Thank you. Do you mean no carbs as in no veg, only fats and meats? What would you expect to see happen, in terms of what response would indicate what? Is type 2 diabetes purely about the glucose in your blood in response to what you have eaten, or is it also about the glucose in your blood because your liver is putting it there? I thought it was the glucose in the blood that does the damage whatever the source of that glucose?I understand from the Handbook that screening for diabetes via fasting plasma glucose does not capture exactly the same population as those diagnosed by HbA1c or OGTT (I don't know (personally) of anyone who was diagnosed via a FPG test).
There are some things that affect HbA1c results (eg anaemia or renal failure). It's viewed as a better test because of low biological variability and because it effectively tests over several weeks. It has diadavantages (according to the handbook) and one is that "some patients and ethnic groups may be diagnosed with diabtetes by some criteria but not others".
Given how many of us do some form of intermittent fasting, and that the point is to lower blood glucose and therefore HbA1c, I wouldn't call that distorting the Hba1c result. It is a count of glycated red blood cells and the IF etc is intended to lower it. Your A1c is roughly where mine has been but my fingerprick readings are mid 4s to low 5s, which is what you might expect.
As well as the Libre accuracy issue, I wonder if you tried a few days without carbs at all to see whether it made any impact? If your numbers fall, then you have a better idea about what's giving you the daily readings.
I don't know how many carbs you're eating at the minute so tried not to be prescriptive. This has worked for me in the past. If you reduce carb intake significantly, whatever that means in your case, you might possibly see some reduction in the current readings - less carb in, less glucose. As I understand it insulin resistance refers to the resistance of the muscle cells only, not fat cells.Thank you. Do you mean no carbs as in no veg, only fats and meats? What would you expect to see happen, in terms of what response would indicate what? Is type 2 diabetes purely about the glucose in your blood in response to what you have eaten, or is it also about the glucose in your blood because your liver is putting it there? I thought it was the glucose in the blood that does the damage whatever the source of that glucose?
My body seems very bad at getting glucose into my cells (as indicated by the lack of energy I have access to) , but really good at turning it into fat and storing it in my body and liver, (as indicated by my weight and NAFL) does insulin resistance mean all cells are resistant to having glucose placed in them, including fat cells, or just the muscle cells which need energy?
I would be happy to eat only veg and fats and proteins for a few days to see what happens, but I’d like to know what different reactions would be signifying?
I was keto for nearly 3 years, trying to treat my M.E but it was a very miserable existence cut off from the communality of sharing food with my family, and when your life is limited to a bed and a house and even socialising with your own child is limited food is one of the only pleasures in life, so even harder to eat keto.
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