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Message: <blockquote data-quote="Oldvatr" data-source="post: 1934153" data-attributes="member: 196898">I note that DIRECT specifically excluded insulin users, but this addendum includes notes about seeing GP etc.  This means that DIRECT cannot be used to prove remission in ID T2D so this addendum should make that clear at the outset.  I note too that DIRECT found that 22% of those in remission at 12 months were back taking diabetic meds again, and the meds for hypertension seems to have increased up again even in the maintenance phase.  Also noted the very quick rise in weight that those dropping out of each phase experienced.  They are keeping stumm about the 9 people that suffered sugnificant adverse reactions to the diet, and those seem to be over and above the 32 that dropped out (>10% dropout rate?)  This is an interim report, and the presentations slides are not definitve so the full report may shed light on these.The report does not give numeric data on those needing secondary intervention with Orlistat(sp ?) or other weight loss assistance.</blockquote>

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