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New study using polypill to reduce Heart problems
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<blockquote data-quote="Oldvatr" data-source="post: 2331476" data-attributes="member: 196898"><p>=Actually, I find my calculations for the percentages reported for the polyfiller+aspirin group work out at half the figures they give us in the abstract, but I agree exacly with those for the other two legs.. I have had to assume that the cohorts for each were the same size else comparison cross legs will not be valid which is a weakness in the 2+2 factorial study methodology. So I get a relative risk reduction of 16% not the 33% that others see and as reported by the authors. I suspect that the poly plus leg had half the sample size of the others since the reported events are approx half the others legs. on the placebo side.</p></blockquote><p></p>
[QUOTE="Oldvatr, post: 2331476, member: 196898"] =Actually, I find my calculations for the percentages reported for the polyfiller+aspirin group work out at half the figures they give us in the abstract, but I agree exacly with those for the other two legs.. I have had to assume that the cohorts for each were the same size else comparison cross legs will not be valid which is a weakness in the 2+2 factorial study methodology. So I get a relative risk reduction of 16% not the 33% that others see and as reported by the authors. I suspect that the poly plus leg had half the sample size of the others since the reported events are approx half the others legs. on the placebo side. [/QUOTE]
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