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<blockquote data-quote="Bluetit1802" data-source="post: 1910134" data-attributes="member: 94045"><p>This is normal withdrawal, and why someone being taken off beta blockers must do it gradually. It wears off after a while by all accounts. Its a shame you can't change types. Have you discussed all this with your doctor?</p><p></p><p><a href="https://www.gpnotebook.co.uk/simplepage.cfm?ID=x20120516081816351223" target="_blank">https://www.gpnotebook.co.uk/simplepage.cfm?ID=x20120516081816351223</a></p><p></p><p>Beta blockers in diabetes and insulin resistance:</p><p></p><ul> <li data-xf-list-type="ul">studies, such as the Losartan Intervention for Endpoint Reduction in Hypertension Study (LIFE) (3) with atenolol, the Carvedilol or Metoprolol European Trial (COMET) (4) with metoprolol have shown a 22% to 28% increase of new-onset diabetes with traditional beta beta-blockers that can increase insulin resistance (and hence hyperglycaemia) (5)</li> <li data-xf-list-type="ul">side effects of beta -blockers in the patient with diabetes include increased insulin resistance with worsening glycemic control</li> <li data-xf-list-type="ul">increased frequency of hypoglycemia and its lack of recognition can also be a problem in the insulin-deficient patient but is a minimal problem with the patient with type 2 diabetes (5)</li> <li data-xf-list-type="ul">there is evidence that some beta-blockers may have 'insulin-sensitising properties' (5)<ul> <li data-xf-list-type="ul">carvedilol, a nonselective beta-blocker had vasodilating and insulin-sensitizing properties, and is the ideal beta-blocker for the patient with diabetes (5)</li> <li data-xf-list-type="ul">carvedilol is a third generation beta-blocker in comparison with atenolol which is a second generation beta blocker</li> </ul></li> </ul></blockquote><p></p>
[QUOTE="Bluetit1802, post: 1910134, member: 94045"] This is normal withdrawal, and why someone being taken off beta blockers must do it gradually. It wears off after a while by all accounts. Its a shame you can't change types. Have you discussed all this with your doctor? [URL]https://www.gpnotebook.co.uk/simplepage.cfm?ID=x20120516081816351223[/URL] Beta blockers in diabetes and insulin resistance: [LIST] [*]studies, such as the Losartan Intervention for Endpoint Reduction in Hypertension Study (LIFE) (3) with atenolol, the Carvedilol or Metoprolol European Trial (COMET) (4) with metoprolol have shown a 22% to 28% increase of new-onset diabetes with traditional beta beta-blockers that can increase insulin resistance (and hence hyperglycaemia) (5) [*]side effects of beta -blockers in the patient with diabetes include increased insulin resistance with worsening glycemic control [*]increased frequency of hypoglycemia and its lack of recognition can also be a problem in the insulin-deficient patient but is a minimal problem with the patient with type 2 diabetes (5) [*]there is evidence that some beta-blockers may have 'insulin-sensitising properties' (5) [LIST] [*]carvedilol, a nonselective beta-blocker had vasodilating and insulin-sensitizing properties, and is the ideal beta-blocker for the patient with diabetes (5) [*]carvedilol is a third generation beta-blocker in comparison with atenolol which is a second generation beta blocker [/LIST] [/LIST] [/QUOTE]
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