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Diabetes Discussion
Reactive Hypoglycemia
Newly diagnosed, is it really RH?
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<blockquote data-quote="kokhongw" data-source="post: 2356807" data-attributes="member: 277199"><p>Perhaps this write-up might give you something to think about...</p><p></p><p>Broadly there's 3 key variables here...</p><p>1) Glucose</p><p>2) Insulin</p><p>3) Ketones</p><p></p><p>For metabolically normal people, Glucose stays around 4.0-6.0 mmol. Insulin/Ketones levels are seldom measured.</p><p></p><p>Our brain is typically fueled by glucose and is an energy hog. If it senses that it is not getting enough energy, it triggers all kinds of responses... </p><p></p><p>One typical model regarding RH is this, carbs triggers excessive insulin, that drives down glucose, so our brain goes into a frenzy...</p><p></p><p><img src="https://www.diabetes.co.uk/forum/attachments/upload_2018-1-20_8-28-39-png.24982/" alt="" class="fr-fic fr-dii fr-draggable " style="" /></p><p></p><p>Hence the idea of going low carbs is to avoid the high insulin responses which we cannot measure, but assumed is happening in the background. Your 3 hour OGTT shows a spike in insulin, but no steep drop in glucose...</p><p></p><p>So the general hypothesis is that with high insulin and low glucose, the brain cannot function properly. Usually, ketones will be produced to fill the energy gap. But high insulin suppresses ketones production. So there's no ketones to the rescue...</p><p></p><p>We can see from 10 days fasting experiments of healthy individual that when glucose/insulin is low, ketones production goes up after 48 hrs or so. This time gap may differ depending on our level of metabolic dysfunction...we may be highly insulin resistant and needs a much longer time for both glucose AND insulin to be low enough for ketones production to ramp up...</p><p></p><p><a href="https://thequantifiedbody.net/10-day-water-fast-results/" target="_blank">https://thequantifiedbody.net/10-day-water-fast-results/</a></p><p><img src="https://thequantifiedbody.net/wp-content/uploads/2016/02/10daywaterfast-ketones-glucose.png" alt="" class="fr-fic fr-dii fr-draggable " style="" /></p><p></p><p></p><p>So in order to deal with RH... glucose/insulin levels needs to stabilize. Then our brain can have a stable flow of energy supply...</p><p></p><p>Libre is a good tool to pick up the peaks and crashes that we may some times missed with finger prick test.</p></blockquote><p></p>
[QUOTE="kokhongw, post: 2356807, member: 277199"] Perhaps this write-up might give you something to think about... Broadly there's 3 key variables here... 1) Glucose 2) Insulin 3) Ketones For metabolically normal people, Glucose stays around 4.0-6.0 mmol. Insulin/Ketones levels are seldom measured. Our brain is typically fueled by glucose and is an energy hog. If it senses that it is not getting enough energy, it triggers all kinds of responses... One typical model regarding RH is this, carbs triggers excessive insulin, that drives down glucose, so our brain goes into a frenzy... [IMG]https://www.diabetes.co.uk/forum/attachments/upload_2018-1-20_8-28-39-png.24982/[/IMG] Hence the idea of going low carbs is to avoid the high insulin responses which we cannot measure, but assumed is happening in the background. Your 3 hour OGTT shows a spike in insulin, but no steep drop in glucose... So the general hypothesis is that with high insulin and low glucose, the brain cannot function properly. Usually, ketones will be produced to fill the energy gap. But high insulin suppresses ketones production. So there's no ketones to the rescue... We can see from 10 days fasting experiments of healthy individual that when glucose/insulin is low, ketones production goes up after 48 hrs or so. This time gap may differ depending on our level of metabolic dysfunction...we may be highly insulin resistant and needs a much longer time for both glucose AND insulin to be low enough for ketones production to ramp up... [URL]https://thequantifiedbody.net/10-day-water-fast-results/[/URL] [IMG]https://thequantifiedbody.net/wp-content/uploads/2016/02/10daywaterfast-ketones-glucose.png[/IMG] So in order to deal with RH... glucose/insulin levels needs to stabilize. Then our brain can have a stable flow of energy supply... Libre is a good tool to pick up the peaks and crashes that we may some times missed with finger prick test. [/QUOTE]
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Newly diagnosed, is it really RH?
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