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NHS Direct doctor says... NO testing when taking Metformin
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<blockquote data-quote="NWCub76" data-source="post: 865670" data-attributes="member: 186419"><p>You're quite correct about metformin and food to avoid stomach upsets, but also because one of it's actions is to reduce the amount of sugar absorbed from the intestines.</p><p>Also, yes, your liver will produce sugar and release it into your blood stream if you don't eat enough or regularly enough. This is also part of the bigger picture in T2 diabetes, as the chemical pathways which lead to the liver producing sugar can be triggered by the muscle cells because they're not absorbing insulin properly, so they call out for more fuel, and the liver responds, sending your blood sugars ever higher!</p><p>Metformin is supposed to help reduce this mechanism by helping the muscles absorb insulin better so they can use the blood sugar more effectively, and thereby reduce the calls on the liver to produce more sugar. It also helps to stop the liver producing more sugar directly by acting on the liver.\</p><p>Sadly, metformin does not seem to be effective for everybody <img src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" class="smilie smilie--sprite smilie--sprite3" alt=":(" title="Frown :(" loading="lazy" data-shortname=":(" />, and is often used in conjunction with gliclazide for this reason.</p></blockquote><p></p>
[QUOTE="NWCub76, post: 865670, member: 186419"] You're quite correct about metformin and food to avoid stomach upsets, but also because one of it's actions is to reduce the amount of sugar absorbed from the intestines. Also, yes, your liver will produce sugar and release it into your blood stream if you don't eat enough or regularly enough. This is also part of the bigger picture in T2 diabetes, as the chemical pathways which lead to the liver producing sugar can be triggered by the muscle cells because they're not absorbing insulin properly, so they call out for more fuel, and the liver responds, sending your blood sugars ever higher! Metformin is supposed to help reduce this mechanism by helping the muscles absorb insulin better so they can use the blood sugar more effectively, and thereby reduce the calls on the liver to produce more sugar. It also helps to stop the liver producing more sugar directly by acting on the liver.\ Sadly, metformin does not seem to be effective for everybody :(, and is often used in conjunction with gliclazide for this reason. [/QUOTE]
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NHS Direct doctor says... NO testing when taking Metformin
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