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Normal hba1c test. Should i get a GADA test too?

Leew86

Newbie
Messages
1
Type of diabetes
Reactive hypoglycemia
Treatment type
Other
Hello
I was recently diagnosed with reactive hypoglycemia. But I'm unconvinced that its the issue. I've had blood sugar below >3 mmol without large meals etc
I have normal blood test results for the HBa1c test. Would a GADA test show anything up that a normal blood test wouldn't? Just want opinions if its worth asking the GP. Or is it a waste of time?
Thanks for any help
 
Hi and welcome to the forum @Leew86 . I’m assuming by a GADA blood test you are talking about Glutamic Acid Decarboxylase Antibodies. What is it that has made you think you may have late onset adult diabetes ((LADA) it’s a sub group of T1 diabetes ? Usually LADA is suspected when blood lowering medications are simply not working and blood sugars are very high. LADA is associated with high blood sugars, simply because the body’s own immune system is destroying insulin producing beta cells so the body cannot produce enough insulin. Beta cells continue to attack the beta cells until there are non left.

Usually a Dr will test your C-peptides first. C- peptides are produced along side insulin. So if your insulin is low, then your C-peptides will be low . C-Peptides are tested rather than insulin as C - peptides remain more stable outside the body for testing.

If it is found you have low C-Peptides alongside high blood sugars , the Dr may then ask for an antibody test. There are five antibody types associated with T1 diabetes , usually you are tested for four .GADA antibodies are the most common alongside a second type of antibody:

Glutamic Acid Decarboxylase Autoantibodies (GADA or Anti-GAD)

Insulin Autoantibodies (IAA)

IA-2A -Associated-2 Autoantibodies (IA-2A)

Zinc Transporter 8 (ZnT8Ab)

Islet Cell Cytoplasmic Autoantibodies (ICA)

If your blood sugars are normal, you may find it hard to convince your Dr to undertake an antibody test. High blood sugars are the main flag indicator for T1-diabetes.

I’ll dig out some information on LADA for you.

Edited to add the following links

https://www.trialnet.org/events-new...taging-classification-opens-door-intervention

https://pmc.ncbi.nlm.nih.gov/articles/PMC5491594/
 
Hello
I was recently diagnosed with reactive hypoglycemia. But I'm unconvinced that its the issue. I've had blood sugar below >3 mmol without large meals etc
I have normal blood test results for the HBa1c test. Would a GADA test show anything up that a normal blood test wouldn't? Just want opinions if its worth asking the GP. Or is it a waste of time?
Thanks for any help
Another welcome to the forum @Leew86 .

How have those lows been measured? CGM, fingerprick or labwork?
Are those lows symptomatic?

An antibodies test like anti GAD is for seeing if existing diabetes is autoimmune (T1).
Diabetes of any type means having high blood glucose, not low. Low BG in diabetics is a result of medication, not of the condition.

There are various possible causes of hypoglycaemia in non diabetics. What tests did you have to diagnose RH?
 
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