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Message: <blockquote data-quote="phoenix" data-source="post: 323791" data-attributes="member: 12578">SarahThere was a UK trial of the drug on people with diabetes, some of whom were taking insulin.At 6 months those who kept taking it were doing OK, they had lost some weight ( average 7kg) and had slightly better HbA1cs  . At six months, those that were on insulin were taking quite a bit less. At 2 years, there were only 23 out of  the original 100 that were still taking it. These people had an average weight loss of  (I think, it's not clear) another 5Kg .   HbA1c hadn't changed, and I can't see if insulin use remained lower. It worked, to a degree,  but   less than a quarter of the people managed to complete the 2 years <a href="http://www.crd.york.ac.uk/CRDWeb/ShowRecord.asp?ID=22006000042" target="_blank">http://www.crd.york.ac.uk/CRDWeb/ShowRe ... 2006000042</a>I would think that your success or not would depend a lot on how much support you  abutre given. You would have to change your diet considerably.The people were taught how  to reduce their fat intake to less than 50g a day. This is very little and, as Ladybird says would be a very  big change from your present diet.</blockquote>

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