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pancreas questiion

cavillas

Member
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6
In 2000 I was seriously ill with viral pancretitis and had a large amoount of my pancreas removed. The surgeon warned me at the time that what was left of my pancreas would deteriorate in about 5 years or so and eventually stop working. As a result of this I have type 1 diabetes. I would like to know though if the pancreas problem would cause problems with enzyme production, anyone have any idea.
 
hello cavillas,

Exocrine pancreatic insufficiency (EPI) is the inability to properly digest food due to a lack of digestive enzymes made by the pancreas. EPI is found in humans afflicted with cystic fibrosis and Shwachman-Diamond Syndrome. It is caused by a progressive loss of the pancreatic cells that make digestive enzymes. Chronic pancreatitis is the most common cause of EPI in humans. Loss of digestive enzymes leads to maldigestion and malabsorption of nutrients.

originally cut and pasted from:
http://en.wikipedia.org/wiki/Pancreas

all the best,
timo.
 
hi cavillas,

The enzymes produced by the pancreas are very important for digestion.
if the exocrine function of you pancreas completely fails then you'll
usually need to take enzyme supplements.

hope this helps
goodluck,
timo.
 
Just in case you're interested:

The beginner's guide to Pancreatic functions

Endocrine function (hormones)

Insulin
causes most of the body's cells to take up glucose from
the blood (including liver, muscle, and fat tissue cells).
It's presence also inhibits the use of fat as an energy source.

Islet Amyloid Polypeptide (amylin)
slows the rate of glucose entering the bloodstream during digestion.
also suppresses the release of glucagon.

Glucagon
causes the liver to convert stored glycogen into glucose(glycogenolysis)

Somatostatin
regulates the endocrine system and affects neurotransmission
and cell proliferation(growth)

Gastrin
stimulates secretion of gastric acid in the stomach

Ghrelin
stimulates appetite

C-peptide
a byproduct of normal insulin production.
functions in repair of the muscular layer of the arteries.


Exocrine function (enzymes)

Trypsin
breaks down protein during digestion

Chymotrypsin
breaks down protein during digestion

Pancreatic Lipase
breaks down fat during digestion

Pancreatic Amylase
breaks down starch during digestion
 
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