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<blockquote data-quote="Winnie53" data-source="post: 2041531" data-attributes="member: 160246"><p>Okay, I used a better search strategy and found the thread that discusses nutrient supplement strategies to reverse neuropathy...</p><p></p><p><a href="https://www.diabetes.co.uk/forum/threads/help-in-dealing-with-neuropathy.74653/" target="_blank">https://www.diabetes.co.uk/forum/threads/help-in-dealing-with-neuropathy.74653/</a></p><p></p><p>It's a 10 page thread. In post #3, Omnipod outlines the results of his research on neuropathy.</p><p></p><p>In post #33, I quoted the most helpful information that forum members shared up until that point.</p><p></p><p>More helpful information likely followed.</p><p></p><p>What I didn't know 4 years ago was that 4 out of 10 people have a genetic variation or mutation of the MTHFR gene. Dr. Will Cole wrote an article that speaks specifically to MTHFR and the B vitamins...</p><p></p><p><em>"One of those genes, called the MTHFR gene, can have a mutation that can specifically interfere with your ability to absorb certain vitamins and detox the body efficiently. About 40% of us have this mutation, myself included, and it can predispose you to health issues. Let’s look at what it’s all about, and especially, what you can do about it." </em></p><p></p><p>At the end the end of the article he gives specific recommendation on what forms of B vitamins are best... <a href="https://drwillcole.com/what-you-need-to-know-about-the-gene-mutation-that-affects-40-of-the-world/" target="_blank">https://drwillcole.com/what-you-need-to-know-about-the-gene-mutation-that-affects-40-of-the-world/</a></p><p></p><p>Something that has confused me for some time is how is it possible that a 29 year old, recently diagnosed with pre-diabetes, could possibly already have diabetic complications? And why have I had to take a B-complex off and on my entire life to feel my best?</p><p></p><p>Answer: The likely cause may be a genetic variation or mutation of the MTHFR gene.</p><p></p><p>B vitamins are very important for brain and nerve health and are often depleted by diabetes. If you have both MTHFR and diabetes, we can begin having problems much sooner than others with diabetes.</p><p></p><p>It's not the whole answer of course, but it's a place to start.</p><p></p><p>There's a facebook support group called TypeOneGrit for type 1 diabetics who use Richard Bernstein's low car diet to manage their glucose levels. For type 2's, the low carb diet forum here and <a href="http://www.dietdoctor.com" target="_blank">www.dietdoctor.com</a> are good place to begin learning about the low carb diet.</p><p></p><p>Some members here, myself included, take 600 mg alpha lipoic acid daily to reduce risk of complications or to reverse complications. Much of the research on reversing diabetic complications has been on using the combination of these two supplements. I've been told that r-alpha lipoic acid works better.</p><p></p><p>Taking a good quality, whole food multivitamin with all the B vitamins was not enough for me. I had a high homocysteine level until I added a B-complex recently. In addition, after I get tested to see if I have the MTHFR variation or mutation, I may add the pre-activated forms of some of the B vitamins to my B-complex.</p><p></p><p>Hope this helps...</p></blockquote><p></p>
[QUOTE="Winnie53, post: 2041531, member: 160246"] Okay, I used a better search strategy and found the thread that discusses nutrient supplement strategies to reverse neuropathy... [URL]https://www.diabetes.co.uk/forum/threads/help-in-dealing-with-neuropathy.74653/[/URL] It's a 10 page thread. In post #3, Omnipod outlines the results of his research on neuropathy. In post #33, I quoted the most helpful information that forum members shared up until that point. More helpful information likely followed. What I didn't know 4 years ago was that 4 out of 10 people have a genetic variation or mutation of the MTHFR gene. Dr. Will Cole wrote an article that speaks specifically to MTHFR and the B vitamins... [I]"One of those genes, called the MTHFR gene, can have a mutation that can specifically interfere with your ability to absorb certain vitamins and detox the body efficiently. About 40% of us have this mutation, myself included, and it can predispose you to health issues. Let’s look at what it’s all about, and especially, what you can do about it." [/I] At the end the end of the article he gives specific recommendation on what forms of B vitamins are best... [URL]https://drwillcole.com/what-you-need-to-know-about-the-gene-mutation-that-affects-40-of-the-world/[/URL] Something that has confused me for some time is how is it possible that a 29 year old, recently diagnosed with pre-diabetes, could possibly already have diabetic complications? And why have I had to take a B-complex off and on my entire life to feel my best? Answer: The likely cause may be a genetic variation or mutation of the MTHFR gene. B vitamins are very important for brain and nerve health and are often depleted by diabetes. If you have both MTHFR and diabetes, we can begin having problems much sooner than others with diabetes. It's not the whole answer of course, but it's a place to start. There's a facebook support group called TypeOneGrit for type 1 diabetics who use Richard Bernstein's low car diet to manage their glucose levels. For type 2's, the low carb diet forum here and [URL='http://www.dietdoctor.com']www.dietdoctor.com[/URL] are good place to begin learning about the low carb diet. Some members here, myself included, take 600 mg alpha lipoic acid daily to reduce risk of complications or to reverse complications. Much of the research on reversing diabetic complications has been on using the combination of these two supplements. I've been told that r-alpha lipoic acid works better. Taking a good quality, whole food multivitamin with all the B vitamins was not enough for me. I had a high homocysteine level until I added a B-complex recently. In addition, after I get tested to see if I have the MTHFR variation or mutation, I may add the pre-activated forms of some of the B vitamins to my B-complex. Hope this helps... [/QUOTE]
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