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<blockquote data-quote="Stephen Lewis" data-source="post: 2043156" data-attributes="member: 479176"><p>I have had ever worsening foot neuropathy for about 8 years beginning with 'deep' itching at night and now having just about all the pain symptoms mentioned earlier. Finally my condition seems to be improving from a wide range of suggestions that I am using. The following are in reverse order of benefit and I will not stop any of them because I do not want any regression.</p><p>1. Ramipril 5 mg 2 times a day. Prescribed for blood pressure because it increases the size of capillaries.</p><p>2. Pregabalin high dose of 150 mg 2 times a day. Only benefit is that it acts on the pain receptors in the brain to ease this symptom. My opinion on drugs for symptoms instead of cures is known in this forum.</p><p>3. About 4 months ago I purchased an electric throw as a way to keep my feet warm as this improves blood flow. I believe the over stimulated nerve pain is a natural warning of an issue that is not damage to the nerves but may cause damage eventually. I use the throw on the bed over the duvet. I turn it on a couple of hours before going to bed. This helps keep the feet warm again to stimulate blood flow.</p><p>4. I walk a lot including gym warm-ups at about 4 m.p.h. After a few minutes it is obvious that there is additional warm blood flow to the lower legs and feet. I know walking can be painful but I find that when the blood starts to flow better, the pain decreases.</p><p>5. On this forum and confirmed by my diabetic clinic is Alpha or R-Alpha Lipoic Acid. I have tried both and find 400 mg 4 times a day is the most beneficial. R-Alpha is better absorbed but is much more expensive and is only available here in 100 mg capsules. The clinic says the maximum dose is 1800 mg per day. I began this high dose only 4 months ago.</p><p>B12 was alos suggested by the clinic but I think this is to counter the negative effects of Metformin on the blood not for neuropathy.</p><p>It certainly feels that finally my condition is slowly improving especially at night and I will keep doing all these things until it disappears or my feet are amputated. Li so much with diabetes we have to find out, often on our own, what works best for each of us. This forum is invaluable to do this.</p><p>Just another comment. I believe the needle test to see if we have any feeling in the feet is either too late or useless. Thenerves in my feet are fine. The slightest thing underfoot even with shoes on such as a slight ridge in the sidewalk (pavement to those outside North America) will cause immediate and very sharp pain. Once I stop feeling this, my condition is either in remission or...</p></blockquote><p></p>
[QUOTE="Stephen Lewis, post: 2043156, member: 479176"] I have had ever worsening foot neuropathy for about 8 years beginning with 'deep' itching at night and now having just about all the pain symptoms mentioned earlier. Finally my condition seems to be improving from a wide range of suggestions that I am using. The following are in reverse order of benefit and I will not stop any of them because I do not want any regression. 1. Ramipril 5 mg 2 times a day. Prescribed for blood pressure because it increases the size of capillaries. 2. Pregabalin high dose of 150 mg 2 times a day. Only benefit is that it acts on the pain receptors in the brain to ease this symptom. My opinion on drugs for symptoms instead of cures is known in this forum. 3. About 4 months ago I purchased an electric throw as a way to keep my feet warm as this improves blood flow. I believe the over stimulated nerve pain is a natural warning of an issue that is not damage to the nerves but may cause damage eventually. I use the throw on the bed over the duvet. I turn it on a couple of hours before going to bed. This helps keep the feet warm again to stimulate blood flow. 4. I walk a lot including gym warm-ups at about 4 m.p.h. After a few minutes it is obvious that there is additional warm blood flow to the lower legs and feet. I know walking can be painful but I find that when the blood starts to flow better, the pain decreases. 5. On this forum and confirmed by my diabetic clinic is Alpha or R-Alpha Lipoic Acid. I have tried both and find 400 mg 4 times a day is the most beneficial. R-Alpha is better absorbed but is much more expensive and is only available here in 100 mg capsules. The clinic says the maximum dose is 1800 mg per day. I began this high dose only 4 months ago. B12 was alos suggested by the clinic but I think this is to counter the negative effects of Metformin on the blood not for neuropathy. It certainly feels that finally my condition is slowly improving especially at night and I will keep doing all these things until it disappears or my feet are amputated. Li so much with diabetes we have to find out, often on our own, what works best for each of us. This forum is invaluable to do this. Just another comment. I believe the needle test to see if we have any feeling in the feet is either too late or useless. Thenerves in my feet are fine. The slightest thing underfoot even with shoes on such as a slight ridge in the sidewalk (pavement to those outside North America) will cause immediate and very sharp pain. Once I stop feeling this, my condition is either in remission or... [/QUOTE]
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