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Physiology of insulin release - know your pancreas
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<blockquote data-quote="Bubbleblower" data-source="post: 2486704" data-attributes="member: 540059"><p>“In conclusion, the pancreatic α/β increased after type 2 diabetes onset and correlated with diabetes duration, while relative alpha-cell area correlated with HbA1c.”</p><p><a href="https://www.researchgate.net/publication/323978222_Human_Pancreatic_Alpha-_to_Beta-Cell_Area_Ratio_Increases_After_Type_2_Diabetes_Onset" target="_blank">Human Pancreatic Alpha- to Beta-Cell Area Ratio Increases After Type 2 Diabetes Onset</a></p><p></p><p>"We observed an eight times increased frequency of insulin cells coexpressing glucagon in donors with diabetes." <a href="https://diabetes.diabetesjournals.org/content/64/8/2928" target="_blank">Loss of β-Cell Identity Occurs in Type 2 Diabetes and Is Associated With Islet Amyloid Deposits</a></p><p></p><p>I wonder what explains these different outcomes, but I am not gonna break my head over it now.</p></blockquote><p></p>
[QUOTE="Bubbleblower, post: 2486704, member: 540059"] “In conclusion, the pancreatic α/β increased after type 2 diabetes onset and correlated with diabetes duration, while relative alpha-cell area correlated with HbA1c.” [URL='https://www.researchgate.net/publication/323978222_Human_Pancreatic_Alpha-_to_Beta-Cell_Area_Ratio_Increases_After_Type_2_Diabetes_Onset']Human Pancreatic Alpha- to Beta-Cell Area Ratio Increases After Type 2 Diabetes Onset[/URL] "We observed an eight times increased frequency of insulin cells coexpressing glucagon in donors with diabetes." [URL='https://diabetes.diabetesjournals.org/content/64/8/2928']Loss of β-Cell Identity Occurs in Type 2 Diabetes and Is Associated With Islet Amyloid Deposits[/URL] I wonder what explains these different outcomes, but I am not gonna break my head over it now. [/QUOTE]
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