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<blockquote data-quote="Melgar" data-source="post: 2716758" data-attributes="member: 520626"><p>[USER=590631]@nabilla[/USER] I can relate to what you are saying. I too am lean, BMI 19 , low normal C-peptides so Insulin Resistance is unlikely, although IR can fluctuate even in healthy none diabetic individuals, but I am not over producing insulin to counter IR. I’m fit, I do 25,000 - 30’000 steps a day, I do weights and resistance training, my RHR is around 62, at night it is in the 50’s. Very low triglycerides , I eat a healthy diet of chicken and fish, I don’t drink or smoke. So where do we go with this. I’m on the same page as you. Now my Dr blows hot and cold on the LADA .,I already have an autoimmune disorder and my brother is Type 1. </p><p></p><p>My advice if you are looking to have some private blood tests to determine what your pancreas is doing would be to check your C-Peptide levels. A cheaper option than antibody tests as they can be pricey and there are four types, not just GAD. There is a direct correlation between insulin and c-peptides. Both insulin and C-peptides are produced by the pancreas. C-peptides are measured rather than insulin as insulin has only a very short shelf life whereas C -peptides are more stable . If you are producing a lot of C-peptides it means you are producing a lot of insulin. High insulin levels in your blood would suggest the pancreas is having to produce a lot of insulin to counter the Insulin Resistance to get the glucose out if your blood and into your cells. High insulin production is associated with Insulin Resistance and Type 2 diabetes. </p><p></p><p>Not wanting to jump the gun here as your blood sugars are only slightly raised, but If you do get your C-peptides tested and your tests show you have low C-peptides then your GP may test for autoimmune antibodies. Although as I say your blood sugars are only slightly raised. There are 4 antibodies types associated with the development of T1DM / LADA, islet cell autoantibodies (ICA), antibodies to insulin (IAA), glutamic acid decarboxylase (GAA or GAD) and protein tyrosine phosphatase (IA2 or ICA512) </p><p>I hope that helps.</p></blockquote><p></p>
[QUOTE="Melgar, post: 2716758, member: 520626"] [USER=590631]@nabilla[/USER] I can relate to what you are saying. I too am lean, BMI 19 , low normal C-peptides so Insulin Resistance is unlikely, although IR can fluctuate even in healthy none diabetic individuals, but I am not over producing insulin to counter IR. I’m fit, I do 25,000 - 30’000 steps a day, I do weights and resistance training, my RHR is around 62, at night it is in the 50’s. Very low triglycerides , I eat a healthy diet of chicken and fish, I don’t drink or smoke. So where do we go with this. I’m on the same page as you. Now my Dr blows hot and cold on the LADA .,I already have an autoimmune disorder and my brother is Type 1. My advice if you are looking to have some private blood tests to determine what your pancreas is doing would be to check your C-Peptide levels. A cheaper option than antibody tests as they can be pricey and there are four types, not just GAD. There is a direct correlation between insulin and c-peptides. Both insulin and C-peptides are produced by the pancreas. C-peptides are measured rather than insulin as insulin has only a very short shelf life whereas C -peptides are more stable . If you are producing a lot of C-peptides it means you are producing a lot of insulin. High insulin levels in your blood would suggest the pancreas is having to produce a lot of insulin to counter the Insulin Resistance to get the glucose out if your blood and into your cells. High insulin production is associated with Insulin Resistance and Type 2 diabetes. Not wanting to jump the gun here as your blood sugars are only slightly raised, but If you do get your C-peptides tested and your tests show you have low C-peptides then your GP may test for autoimmune antibodies. Although as I say your blood sugars are only slightly raised. There are 4 antibodies types associated with the development of T1DM / LADA, islet cell autoantibodies (ICA), antibodies to insulin (IAA), glutamic acid decarboxylase (GAA or GAD) and protein tyrosine phosphatase (IA2 or ICA512) I hope that helps. [/QUOTE]
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