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Progressed onto Insulin - is it reversible?
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<blockquote data-quote="stevew242" data-source="post: 2133253" data-attributes="member: 514165"><p>Interestingly, one meal a day didn't mean ketones when I first started that regime over 5 years ago as I started the day with a surge of glucose thanks to dawn phenomenon and a lot of resistance. It was only when glucose levels started to come down as I appeared to "empty out" of glucose that I got into ketosis. When I reached the peak of post-diabetes health around 2014, glucose was low and I was in ketosis a fair amount of the time. Nobody was worried as all biomarkers ok, HbA1c all non-diabetic etc.</p><p></p><p>What has happened this time around is that I've been eating poorly, allowing things in that I used to be strict about and I'd allowed myself to have beers instead of wine when I drank because I decided I missed it and was too fed up to resist. I'd estimate that for most of the last 12 months I'd probably had 100g of carbs at least and glucose levels started around 17mmol/l and rarely dropped below 14. All of this probably should have meant weight gain, but it didn't -for most of the year my weight remained stable and then in the last two months I reckon I'd lost a stone without trying. Weight loss normally happens due to low insulin, and although I had lost weight due to work stress in the past, I felt different this time. So, I got some ketone test strips to see what was going on 2.2 mmol/l at the same time as BG of 17. For an experiment, I bought a sandwhich to give myself about 40g carbs (this was before any insulin prescribed), ate it and waited for an hour or so and measured again. Ketones were at about 1.8 and BG had risen to 20. The nurses say they're treating me as late onset type 1 for the moment as the symptoms present like that. They're keen to see if the ketones can be brought down, which are hovering around 0.5 most the time now even if I have carbs with a meal and inject, even though BG still above 10 much of the time. If I miss the overnight humulin I dosage after eating 40g carbs and using rapid acting, I go back up towards 2 mmol/l pretty quickly along with 17mmol/l for BG. The key thing is that this never used to be the case and due to insulin resistance (and high circulating insulin) it was always a real struggle to get into ketosis - now it seems hard to get out. </p><p></p><p>Something has definitely changed and for some reason I think my pancreas has shut down partially at least. I suspect I've pushed my luck too far and it probably won't recover. I had hoped that someone may have had a similar experience of managing to achieve remission twice I suppose. It all is the same as when I was first diagnosed but I was able to get myself off everything then and achieve good control if I was sensible.</p><p></p><p>At the moment, I'm not aiming to be ketogenic as I'm just going along with what I'm being asked to do. I've mentioned it as something that worked very well in the past. When I get stability and a bit more info on what's going on (and feel better), I'm going to try it again as a way of getting more weight off in a deliberate, controlled way rather than it happening despite doing things that should make it unlikely. I'm basically hoping that having been stupid, I can pull myself back together.</p></blockquote><p></p>
[QUOTE="stevew242, post: 2133253, member: 514165"] Interestingly, one meal a day didn't mean ketones when I first started that regime over 5 years ago as I started the day with a surge of glucose thanks to dawn phenomenon and a lot of resistance. It was only when glucose levels started to come down as I appeared to "empty out" of glucose that I got into ketosis. When I reached the peak of post-diabetes health around 2014, glucose was low and I was in ketosis a fair amount of the time. Nobody was worried as all biomarkers ok, HbA1c all non-diabetic etc. What has happened this time around is that I've been eating poorly, allowing things in that I used to be strict about and I'd allowed myself to have beers instead of wine when I drank because I decided I missed it and was too fed up to resist. I'd estimate that for most of the last 12 months I'd probably had 100g of carbs at least and glucose levels started around 17mmol/l and rarely dropped below 14. All of this probably should have meant weight gain, but it didn't -for most of the year my weight remained stable and then in the last two months I reckon I'd lost a stone without trying. Weight loss normally happens due to low insulin, and although I had lost weight due to work stress in the past, I felt different this time. So, I got some ketone test strips to see what was going on 2.2 mmol/l at the same time as BG of 17. For an experiment, I bought a sandwhich to give myself about 40g carbs (this was before any insulin prescribed), ate it and waited for an hour or so and measured again. Ketones were at about 1.8 and BG had risen to 20. The nurses say they're treating me as late onset type 1 for the moment as the symptoms present like that. They're keen to see if the ketones can be brought down, which are hovering around 0.5 most the time now even if I have carbs with a meal and inject, even though BG still above 10 much of the time. If I miss the overnight humulin I dosage after eating 40g carbs and using rapid acting, I go back up towards 2 mmol/l pretty quickly along with 17mmol/l for BG. The key thing is that this never used to be the case and due to insulin resistance (and high circulating insulin) it was always a real struggle to get into ketosis - now it seems hard to get out. Something has definitely changed and for some reason I think my pancreas has shut down partially at least. I suspect I've pushed my luck too far and it probably won't recover. I had hoped that someone may have had a similar experience of managing to achieve remission twice I suppose. It all is the same as when I was first diagnosed but I was able to get myself off everything then and achieve good control if I was sensible. At the moment, I'm not aiming to be ketogenic as I'm just going along with what I'm being asked to do. I've mentioned it as something that worked very well in the past. When I get stability and a bit more info on what's going on (and feel better), I'm going to try it again as a way of getting more weight off in a deliberate, controlled way rather than it happening despite doing things that should make it unlikely. I'm basically hoping that having been stupid, I can pull myself back together. [/QUOTE]
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