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Progressed onto Insulin - is it reversible?
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<blockquote data-quote="ert" data-source="post: 2133287" data-attributes="member: 504712"><p>So, my questions are:</p><p>1. Has anyone else had this experience and been able to get themselves off insulin for a second time, or is it likely I have finally killed my pancreas? The literature on beta cell recovery seems mixed, with some suggesting that 10 years is probably the point of no return.</p><p></p><p>2. I suspect that I'm still pretty insulin resistant (although I seem to respond to the humolog well), so am reluctant to accept carbs. Before this all started, I was considering the carnivore diet and fasting to drop more weight to finally nail the problem but don't know whether to hang fire on this until things have stabalised. I feel incredibly tired most of the time and am hoping this will resolve now once stablity returns.</p><p></p><p>3. It seems my body is determined to return my BG to 17 in the morning, regardless of evening insulin dosage (including none), although it's slowly edging down. Is it possible that the "set point" is now just too high and that slowly I'll be able to adjust it as lower BGs become normal?</p></blockquote><p>Your consultant should use a c-peptide and insulin resistance result to see whether you can come off insulin. For example, my c-peptide is 0.078 nmol/l (normal is above 0.26) which means I'm not making any so I have no hope in hell in coming off insulin. My HOMA IR is 0.5 (IR is above 1) which means I'm not insulin resistant which is supported by my basal as 5 units split between morning and night.</p><p>[/QUOTE]</p>
[QUOTE="ert, post: 2133287, member: 504712"] So, my questions are: 1. Has anyone else had this experience and been able to get themselves off insulin for a second time, or is it likely I have finally killed my pancreas? The literature on beta cell recovery seems mixed, with some suggesting that 10 years is probably the point of no return. 2. I suspect that I'm still pretty insulin resistant (although I seem to respond to the humolog well), so am reluctant to accept carbs. Before this all started, I was considering the carnivore diet and fasting to drop more weight to finally nail the problem but don't know whether to hang fire on this until things have stabalised. I feel incredibly tired most of the time and am hoping this will resolve now once stablity returns. 3. It seems my body is determined to return my BG to 17 in the morning, regardless of evening insulin dosage (including none), although it's slowly edging down. Is it possible that the "set point" is now just too high and that slowly I'll be able to adjust it as lower BGs become normal? [/QUOTE] Your consultant should use a c-peptide and insulin resistance result to see whether you can come off insulin. For example, my c-peptide is 0.078 nmol/l (normal is above 0.26) which means I'm not making any so I have no hope in hell in coming off insulin. My HOMA IR is 0.5 (IR is above 1) which means I'm not insulin resistant which is supported by my basal as 5 units split between morning and night. [/QUOTE]
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